Objectives: Comprehensive care is fundamental to cancer survivors enduring long-term side-effects of cancer treatment including nutrition impact symptoms and critical weight loss (CWL). The aim of our study was to address weight loss (WL), nutritional aspects, and quality of life (QoL) in head and neck cancer (HNC) survivors. Study Design: This was a cross-sectional study of HNC patients treated at the Sapienza University-Hospital, 2018-2022. We administered a modified version of the EORTC-QLQ-H&N35, the National Health and Nutrition Examination Survey for taste disorders, and the Fox Questionnaire for dry mouth. WL was recorded at T0 (before cancer treatment), T1 (right after treatment), and (at follow-up) T2. Results: All patients (n = 63; 61.9% males) had a median WL of 16.7% (range: 1.4%-44.2%) at T1 and a median of 9.8% (range: 1.8%-45.6%) at T2. Patients with dysgeusia, poor dentition, and those who underwent major orofacial surgery had the highest WL (P < .05). Patients who received multiple treatment regimens had a higher WL compared to those receiving fewer regimens (P < .05). Patients with nutritional problems (71.4%) had a lower QoL throughout (P < .05). Conclusions: CWL is an important side effect of HNC treatment and may particularly affect survivors with xerostomia/dysgeusia, poor dentition, and those receiving multiple treatment regimens.

Weight loss, nutritional aspects and quality of life in head and neck cancer survivors / Fantozzi, Paolo Junior; Bruno, Federica; Pampena, Riccardo; Reilly, Maegan; Carta, Beatrice; Stendardo, Veronica; Cunicella, Giorgia; Monaca, Marco Della; Tenore, Gianluca; De Felice, Francesca; Valentini, Valentino; Polimeni, Antonella; Romeo, Umberto; Villa, Alessandro. - In: ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY AND ORAL RADIOLOGY. - ISSN 2212-4403. - (2024). [10.1016/j.oooo.2024.10.255]

Weight loss, nutritional aspects and quality of life in head and neck cancer survivors

Fantozzi, Paolo Junior
Primo
Writing – Original Draft Preparation
;
Bruno, Federica
Secondo
;
Carta, Beatrice;Stendardo, Veronica;Cunicella, Giorgia;Monaca, Marco Della;Tenore, Gianluca;De Felice, Francesca;Valentini, Valentino;Polimeni, Antonella;Romeo, Umberto
Penultimo
;
2024

Abstract

Objectives: Comprehensive care is fundamental to cancer survivors enduring long-term side-effects of cancer treatment including nutrition impact symptoms and critical weight loss (CWL). The aim of our study was to address weight loss (WL), nutritional aspects, and quality of life (QoL) in head and neck cancer (HNC) survivors. Study Design: This was a cross-sectional study of HNC patients treated at the Sapienza University-Hospital, 2018-2022. We administered a modified version of the EORTC-QLQ-H&N35, the National Health and Nutrition Examination Survey for taste disorders, and the Fox Questionnaire for dry mouth. WL was recorded at T0 (before cancer treatment), T1 (right after treatment), and (at follow-up) T2. Results: All patients (n = 63; 61.9% males) had a median WL of 16.7% (range: 1.4%-44.2%) at T1 and a median of 9.8% (range: 1.8%-45.6%) at T2. Patients with dysgeusia, poor dentition, and those who underwent major orofacial surgery had the highest WL (P < .05). Patients who received multiple treatment regimens had a higher WL compared to those receiving fewer regimens (P < .05). Patients with nutritional problems (71.4%) had a lower QoL throughout (P < .05). Conclusions: CWL is an important side effect of HNC treatment and may particularly affect survivors with xerostomia/dysgeusia, poor dentition, and those receiving multiple treatment regimens.
2024
Weight loss; head and neck cancer; nutrition; oral medicine; dentistry;
01 Pubblicazione su rivista::01a Articolo in rivista
Weight loss, nutritional aspects and quality of life in head and neck cancer survivors / Fantozzi, Paolo Junior; Bruno, Federica; Pampena, Riccardo; Reilly, Maegan; Carta, Beatrice; Stendardo, Veronica; Cunicella, Giorgia; Monaca, Marco Della; Tenore, Gianluca; De Felice, Francesca; Valentini, Valentino; Polimeni, Antonella; Romeo, Umberto; Villa, Alessandro. - In: ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY AND ORAL RADIOLOGY. - ISSN 2212-4403. - (2024). [10.1016/j.oooo.2024.10.255]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1730078
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