Pharmacological evaluation showed that AEOM significantly reduced pain in an animal model, suggesting potential analgesic properties. Acute toxicity studies indicated no adverse effects on kidney and liver function or blood parameters at doses up to 800 mg/kg. The analgesic effect is likely mediated by flavonoids in the extract, which may inhibit pain pathways. These findings suggest that O. majorana has promising therapeutic applications, particularly as a natural analgesic agent.
Analysis of chemical composition, antioxidant capacity, acute toxicity, and antinociceptive properties of aqueous extract of origanum majorana L / Ahmed El Amiri, My; Kabdy, Hamid; Aitbaba, Abdelfatah; Laadraoui, Jawad; Aboufatima, Rachida; El Yazouli, Loubna; Abdelmounaim, Baslam; Moubtakir, Soad; Garzoli, Stefania; Abderrahman, Chait. - In: CHEMISTRY & BIODIVERSITY. - ISSN 1612-1872. - (2024). [10.1002/cbdv.202401580]
Analysis of chemical composition, antioxidant capacity, acute toxicity, and antinociceptive properties of aqueous extract of origanum majorana L.
Stefania Garzoli
Penultimo
;
2024
Abstract
Pharmacological evaluation showed that AEOM significantly reduced pain in an animal model, suggesting potential analgesic properties. Acute toxicity studies indicated no adverse effects on kidney and liver function or blood parameters at doses up to 800 mg/kg. The analgesic effect is likely mediated by flavonoids in the extract, which may inhibit pain pathways. These findings suggest that O. majorana has promising therapeutic applications, particularly as a natural analgesic agent.| File | Dimensione | Formato | |
|---|---|---|---|
|
El Amiri_Analysis_2022.pdf
accesso aperto
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Creative commons
Dimensione
675.57 kB
Formato
Adobe PDF
|
675.57 kB | Adobe PDF |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
