Fetal Alcohol Spectrum Disorders (FASD) encompass a spectrum of clinical manifestations resulting from maternal alcohol consumption during pregnancy. This condition presents with diverse anomalies including intrauterine and extrauterine growth retardation, phenotypic abnormalities, cerebral structural anomalies, cognitive delays, and behavioral abnormalities. Regrettably, FASD remains an irreversible and epigenetic condition, with total abstention from alcohol during pregnancy being the sole effective preventive measure due to the absence of a viable therapy. Diagnosis typically occurs postnatally, based on a combination of alcohol exposure history and the presence of aforementioned physical or behavioral abnormalities. The diagnosis is not always easy to make even in the post-natal period due to the different subtypes of existing FASD. Indeed, only some of these subtypes cause behavioral or neurodevelopmental abnormalities in the absence of pathognomic physical anomalies. Although the diagnostic criteria are useful, unfortunately, there is a heterogeneity resulting from the different guidelines that are used in different countries. The aim of our review, based on a literature search of online databases including Medline, Medline Complete, PubMed, and Google Scholar, is therefore to provide an overview of the diagnostic criteria used in Italy.

Italian guidelines for the diagnosis and treatment of fetal alcohol spectrum disorders: diagnostic criteria / Micangeli, Ginevra; Menghi, Michela; Paparella, Roberto; Ceccanti, Mauro; Coriale, Giovanna; Fiorentino, Daniela; Ferraguti, Giampiero; Fiore, Marco; Tarani, Luigi; Istat, Iss; Sitac, Aidefad; FIMMG-LAZIO, Sifasd; Simpesv, Sipps; Cipe, ; Study Groups Sapienza, Interdisciplinary; Venditti, Sabrina. - In: RIVISTA DI PSICHIATRIA. - ISSN 2038-2502. - 59:5(2024). [10.1708/4360.43509]

Italian guidelines for the diagnosis and treatment of fetal alcohol spectrum disorders: diagnostic criteria

Ginevra Micangeli;Michela Menghi;Roberto Paparella;Mauro Ceccanti;Giovanna Coriale;Daniela Fiorentino;Giampiero Ferraguti;Marco Fiore;Luigi Tarani
;
Sabrina Venditti
Membro del Collaboration Group
2024

Abstract

Fetal Alcohol Spectrum Disorders (FASD) encompass a spectrum of clinical manifestations resulting from maternal alcohol consumption during pregnancy. This condition presents with diverse anomalies including intrauterine and extrauterine growth retardation, phenotypic abnormalities, cerebral structural anomalies, cognitive delays, and behavioral abnormalities. Regrettably, FASD remains an irreversible and epigenetic condition, with total abstention from alcohol during pregnancy being the sole effective preventive measure due to the absence of a viable therapy. Diagnosis typically occurs postnatally, based on a combination of alcohol exposure history and the presence of aforementioned physical or behavioral abnormalities. The diagnosis is not always easy to make even in the post-natal period due to the different subtypes of existing FASD. Indeed, only some of these subtypes cause behavioral or neurodevelopmental abnormalities in the absence of pathognomic physical anomalies. Although the diagnostic criteria are useful, unfortunately, there is a heterogeneity resulting from the different guidelines that are used in different countries. The aim of our review, based on a literature search of online databases including Medline, Medline Complete, PubMed, and Google Scholar, is therefore to provide an overview of the diagnostic criteria used in Italy.
2024
alcohol-related birth defects; fetal alcohol spectrum disorders; fetal alcohol syndrome; pediatrician; prenatal alcohol exposure
01 Pubblicazione su rivista::01a Articolo in rivista
Italian guidelines for the diagnosis and treatment of fetal alcohol spectrum disorders: diagnostic criteria / Micangeli, Ginevra; Menghi, Michela; Paparella, Roberto; Ceccanti, Mauro; Coriale, Giovanna; Fiorentino, Daniela; Ferraguti, Giampiero; Fiore, Marco; Tarani, Luigi; Istat, Iss; Sitac, Aidefad; FIMMG-LAZIO, Sifasd; Simpesv, Sipps; Cipe, ; Study Groups Sapienza, Interdisciplinary; Venditti, Sabrina. - In: RIVISTA DI PSICHIATRIA. - ISSN 2038-2502. - 59:5(2024). [10.1708/4360.43509]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1725559
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