Epithelial cell tissues have a slow relaxation dynamics resembling that of supercooled liquids. Yet, they also have distinguishing features. These include an extended short-time subdiffusive transient, as observed in some experiments and recent studies of model systems, and a sub-Arrhenius dependence of the relaxation time on temperature, as reported in numerical studies. Here we demonstrate that the anomalous glassy dynamics of epithelial tissues originates from the emergence of a fractal-like energy landscape, particles becoming virtually free to diffuse in specific phase space directions up to a small distance. Furthermore, we clarify that the stiffness of the cells tunes this anomalous behavior, tissues of stiff cells having conventional glassy relaxation dynamics.

Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues / Li, Yan-Wei; Wei, Leon Loh Yeong; Paoluzzi, Matteo; Ciamarra, Massimo Pica. - In: PHYSICAL REVIEW. E. - ISSN 2470-0045. - 103:2(2021). [10.1103/physreve.103.022607]

Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues

Paoluzzi, Matteo;
2021

Abstract

Epithelial cell tissues have a slow relaxation dynamics resembling that of supercooled liquids. Yet, they also have distinguishing features. These include an extended short-time subdiffusive transient, as observed in some experiments and recent studies of model systems, and a sub-Arrhenius dependence of the relaxation time on temperature, as reported in numerical studies. Here we demonstrate that the anomalous glassy dynamics of epithelial tissues originates from the emergence of a fractal-like energy landscape, particles becoming virtually free to diffuse in specific phase space directions up to a small distance. Furthermore, we clarify that the stiffness of the cells tunes this anomalous behavior, tissues of stiff cells having conventional glassy relaxation dynamics.
2021
Statistical Mechanics, Soft Matter, Biological Tissues, Glassy Dynamics
01 Pubblicazione su rivista::01a Articolo in rivista
Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues / Li, Yan-Wei; Wei, Leon Loh Yeong; Paoluzzi, Matteo; Ciamarra, Massimo Pica. - In: PHYSICAL REVIEW. E. - ISSN 2470-0045. - 103:2(2021). [10.1103/physreve.103.022607]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1721267
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