Epithelial cell tissues have a slow relaxation dynamics resembling that of supercooled liquids. Yet, they also have distinguishing features. These include an extended short-time subdiffusive transient, as observed in some experiments and recent studies of model systems, and a sub-Arrhenius dependence of the relaxation time on temperature, as reported in numerical studies. Here we demonstrate that the anomalous glassy dynamics of epithelial tissues originates from the emergence of a fractal-like energy landscape, particles becoming virtually free to diffuse in specific phase space directions up to a small distance. Furthermore, we clarify that the stiffness of the cells tunes this anomalous behavior, tissues of stiff cells having conventional glassy relaxation dynamics.

Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues / Li, Yan-Wei; Wei, Leon Loh Yeong; Paoluzzi, Matteo; Ciamarra, Massimo Pica. - In: PHYSICAL REVIEW. E. - ISSN 2470-0045. - 103:2(2021), pp. 1-9. [10.1103/physreve.103.022607]

Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues

Paoluzzi, Matteo;
2021

Abstract

Epithelial cell tissues have a slow relaxation dynamics resembling that of supercooled liquids. Yet, they also have distinguishing features. These include an extended short-time subdiffusive transient, as observed in some experiments and recent studies of model systems, and a sub-Arrhenius dependence of the relaxation time on temperature, as reported in numerical studies. Here we demonstrate that the anomalous glassy dynamics of epithelial tissues originates from the emergence of a fractal-like energy landscape, particles becoming virtually free to diffuse in specific phase space directions up to a small distance. Furthermore, we clarify that the stiffness of the cells tunes this anomalous behavior, tissues of stiff cells having conventional glassy relaxation dynamics.
2021
statistical mechanics; soft matter; biological tissues; glassy dynamics
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Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues / Li, Yan-Wei; Wei, Leon Loh Yeong; Paoluzzi, Matteo; Ciamarra, Massimo Pica. - In: PHYSICAL REVIEW. E. - ISSN 2470-0045. - 103:2(2021), pp. 1-9. [10.1103/physreve.103.022607]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1721267
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