Objective: We investigated the periodontal status in a group of type 2 diabetes subjects.abstract_31949. A case-control study (1:2) was designed. Materials and Methods: 71 (31 M and 40 F) subjects affected by type 2 diabetes, with an onset of the disease at least four years, (D) were selected and compared to randomly selected controls paired for age and sex (C). Individuals with less than 6 teeth present (out of a maximum of 28 teeth) were not included in the study. Descriptive statistics were performed; data were analysed using logistic regression. Several variables were considered as risk predictors for diabetes: age, smoking habits (SH), gingival conditions (presence of plaque -PP-, calculus –CPand bleeding at probing- B), the number and percentage of periodontal pockets, the level of periodontal disease, the presence of Prevotella intermedia (Pi), Porphyromonas gengivalis (Pg), Bacteroides forshytus (Bf) detected using a PCR assays. Furthermore, as regards D patients, overnight fasting plasma glucose and haemoglobin A1c as markers of the diabetic status and degree of glycemic control were assessed. Multiple regression analysis was used on this group to explicate the role of glycemic control on periodontal disease. Results: 20.0% of the D patients had glycosylated haemoglobin >9. In D group gingival conditions were more severe OR=2.4 CI95%=1.02-5.5 for PP, OR=1.8 CI95%=1.0-3.5 for B, OR=1.5 CI95%=0.85-2.7. Multiple regression showed that the age of the patients (p=0.08) and gingival conditions (p<0.01) gave a significant contribution to the level of periodontitis. Diabetic individuals had a significantly poor gingival conditions (OR=1.3 CI95%=1.1-1.5) and a higher Bf prevalence (OR=1.2 CI95%=1.2-1.8) than those without diabetes while prevalence of periodontitis was not significantly (OR=1.7 CI95%=0.7-2.5). Conclusion: Significant evidence about an association with type 2 diabetes mellitus and periodontal disease was not detected in our study.
Periodontal Conditions in Type 2 Diabetes in an Italian Population. A Case Control / Campus, Guglielmo Giuseppe; Salem, A.; Milia, Egle Patrizia; Baldoni, E.; Lugliè, Pietrina Francesca. - (2003). (Intervento presentato al convegno iadr tenutosi a Goteborg).
Periodontal Conditions in Type 2 Diabetes in an Italian Population. A Case Control
CAMPUS, Guglielmo Giuseppe;E. BALDONI;
2003
Abstract
Objective: We investigated the periodontal status in a group of type 2 diabetes subjects.abstract_31949. A case-control study (1:2) was designed. Materials and Methods: 71 (31 M and 40 F) subjects affected by type 2 diabetes, with an onset of the disease at least four years, (D) were selected and compared to randomly selected controls paired for age and sex (C). Individuals with less than 6 teeth present (out of a maximum of 28 teeth) were not included in the study. Descriptive statistics were performed; data were analysed using logistic regression. Several variables were considered as risk predictors for diabetes: age, smoking habits (SH), gingival conditions (presence of plaque -PP-, calculus –CPand bleeding at probing- B), the number and percentage of periodontal pockets, the level of periodontal disease, the presence of Prevotella intermedia (Pi), Porphyromonas gengivalis (Pg), Bacteroides forshytus (Bf) detected using a PCR assays. Furthermore, as regards D patients, overnight fasting plasma glucose and haemoglobin A1c as markers of the diabetic status and degree of glycemic control were assessed. Multiple regression analysis was used on this group to explicate the role of glycemic control on periodontal disease. Results: 20.0% of the D patients had glycosylated haemoglobin >9. In D group gingival conditions were more severe OR=2.4 CI95%=1.02-5.5 for PP, OR=1.8 CI95%=1.0-3.5 for B, OR=1.5 CI95%=0.85-2.7. Multiple regression showed that the age of the patients (p=0.08) and gingival conditions (p<0.01) gave a significant contribution to the level of periodontitis. Diabetic individuals had a significantly poor gingival conditions (OR=1.3 CI95%=1.1-1.5) and a higher Bf prevalence (OR=1.2 CI95%=1.2-1.8) than those without diabetes while prevalence of periodontitis was not significantly (OR=1.7 CI95%=0.7-2.5). Conclusion: Significant evidence about an association with type 2 diabetes mellitus and periodontal disease was not detected in our study.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
