Digital PET for recurrent prostate cancer: how the technology help

Digital PET is characterized by high sensitivity, spatial and temporal resolution, with growing applications of this technology both in clinical practice and in research settings. Further studies are needed, but the role of digital PET imaging in recurrent prostate cancer is promising, especially in terms of increasing detection rate of the disease. The aim of this mini-review is to provide a general overview of digital PET imaging in recurrent prostate cancer field, by describing the published results and by discussing the open question related to known advantages and eventual disadvantages of using this novel technology. Literature findings concerning Digital PET in recurrent prostate cancer field have been described and discussed, including comparative studies between Analogue and Digital PET scanners; pitfalls in the interpretation of Digital scan, identified in the literature's data extracted, have been presented. Moreover, this review discusses open questions concerning acquisition and reconstruction protocols of Digital scans with tracers used in prostate cancer imaging.