Dialysis and adsorption units are commonly used in liver support devices for the removal of albumin-bound toxins, such as bilirubin, and water-soluble low-molecular-weight toxins, such as creatinine. In this paper, the consolidated approach of chemical engineers' to process design is applied to the analysis of the performance of a MARS treatment. The theoretical analysis of the detoxification process is used to discuss some clinical data obtained during a MARS treatment session, referring to bilirubin and creatinine concentration in plasma and different parts of the device circuit.
Molecular Adsorbent Recirculating System (MARS): a Chemical Engineering Analysis of In Vivo Experimental Data / Annesini, M.C., Morabito, V.E., Novelli, G., Piemonte, V., Turchetti, L.. - 17:(2009), pp. 1095-1100. (9th International Conference on Chemical and Process Engineering Rome MAY 10-13, 2009) [10.3303/cet0917183].
Molecular Adsorbent Recirculating System (MARS): a Chemical Engineering Analysis of In Vivo Experimental Data
ANNESINI, Maria Cristina;MORABITO, VINCENZO EMILIANO;NOVELLI, Gilnardo;PIEMONTE, Vincenzo;TURCHETTI, Luca
2009
Abstract
Dialysis and adsorption units are commonly used in liver support devices for the removal of albumin-bound toxins, such as bilirubin, and water-soluble low-molecular-weight toxins, such as creatinine. In this paper, the consolidated approach of chemical engineers' to process design is applied to the analysis of the performance of a MARS treatment. The theoretical analysis of the detoxification process is used to discuss some clinical data obtained during a MARS treatment session, referring to bilirubin and creatinine concentration in plasma and different parts of the device circuit.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
