The apoplast is one of the first cellular compartments outside the plasma membrane encountered by phytopathogenic microbes in the early stages of plant tissue invasion. Plants have developed sophisticated surveillance mechanisms to sense danger events at the cell surface and promptly activate immunity. However, a fine tuning of the activation of immune pathways is necessary to mount a robust and effective defense response. Several endogenous proteins and enzymes are synthesized as inactive precursors, and their post-translational processing has emerged as a critical mechanism for triggering alarms in the apoplast. In this review, we focus on the precursors of phytocytokines, cell wall remodeling enzymes, and proteases. The physiological events that convert inactive precursors into immunomodulatory active peptides or enzymes are described. This review also explores the functional synergies among phytocytokines, cell wall damage-associated molecular patterns, and remodeling, highlighting their roles in boosting extracellular immunity and reinforcing defenses against pests.

Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity / Del Corpo, D.; Coculo, D.; Greco, M.; De Lorenzo, G.; Lionetti, V.. - In: PLANT COMMUNICATIONS. - ISSN 2590-3462. - (2024). [10.1016/j.xplc.2024.100931]

Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity

Del Corpo D.
Primo
;
Coculo D.
Secondo
;
Greco M.;De Lorenzo G.
Penultimo
;
Lionetti V.
Ultimo
2024

Abstract

The apoplast is one of the first cellular compartments outside the plasma membrane encountered by phytopathogenic microbes in the early stages of plant tissue invasion. Plants have developed sophisticated surveillance mechanisms to sense danger events at the cell surface and promptly activate immunity. However, a fine tuning of the activation of immune pathways is necessary to mount a robust and effective defense response. Several endogenous proteins and enzymes are synthesized as inactive precursors, and their post-translational processing has emerged as a critical mechanism for triggering alarms in the apoplast. In this review, we focus on the precursors of phytocytokines, cell wall remodeling enzymes, and proteases. The physiological events that convert inactive precursors into immunomodulatory active peptides or enzymes are described. This review also explores the functional synergies among phytocytokines, cell wall damage-associated molecular patterns, and remodeling, highlighting their roles in boosting extracellular immunity and reinforcing defenses against pests.
2024
apoplast; cell wall; cell-wall remodeling enzymes; immunity activation; phytocytokines; phytopathogenic microbes; plant immunity; post-translational processing; pro-enzymes; pro-peptides; proteases
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity / Del Corpo, D.; Coculo, D.; Greco, M.; De Lorenzo, G.; Lionetti, V.. - In: PLANT COMMUNICATIONS. - ISSN 2590-3462. - (2024). [10.1016/j.xplc.2024.100931]
File allegati a questo prodotto
File Dimensione Formato  
DelCorpo_Pull_2024.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 3.25 MB
Formato Adobe PDF
3.25 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1714018
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 3
social impact