Evaluation of the Effect of Pistacia atlantica Oleoresin on Blood Sugar, Pressure and Lipids in Patients With Type 2 Diabetes: A Single-Blind, Placebo-Controlled Trial

Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterised by high blood sugar (BS) levels due to im- paired insulin production or insulin resistance. It is a global health concern with significant implications for morbidity and mortality. Persian medicine has long utilised natural remedies, such as Pistacia atlantica Desf., for various diseases. In this ran- domised clinical trial, the effects of P. atlantica oleoresin in the improvement of lipid profiles, glucose indices and blood pressure (BP) were assessed in patients with Type 2 DM. Materials and Methods: In this randomised, single-blind, placebo-controlled study, 42 patients with Type 2 DM were ran- domly allocated to receive either P. atlantica oleoresin or placebo capsule for 3 months. Patients were evaluated prior to and 12 weeks after the beginning of the intervention, in terms of changes in lipid profiles, glucose indices and BP. Results: After 3 months, the mean BP in patients with DM receiving P. atlantica oleoresin was sign