Backgrounds: Takotsubo syndrome (TTS) is an intriguing clinical entity characterized by transient myocardial dysfunction. The precise pathophysiological mechanism of TTS is still unknown, but recent evidence suggests a central role of systemic inflammation associated with adrenergic discharge. Although initially considered benign, TTS has shown several potential short-term and long-term complications and adverse outcomes. To improve understanding and management, advanced cardiovascular magnetic resonance (CMR) techniques, such as feature tracking (FT) and parametric mapping, have gained attention. Purpose of Review: The purpose of this review is to summarize the current literature on the clinical applications of CMR-FT and mapping in TTS. Additionally, the most significant and recent findings will be discussed. Recent Findings: FT-CMR enables the parametric quantification of myocardial deformation, allowing a comprehensive evaluation of left ventricular, right ventricular, and atrial function. It provides an accurate definition of areas of myocardial dysfunction and potentially serves as a superior prognostic tool compared to ejection fraction. Tissue mapping techniques enable precise and comprehensive tissue characterization by quantifying areas of oedema, and myocardial fibrosis. Summary: FT-CMR and mapping techniques serve as valuable prognostic tools both in the acute and chronic phases of TTS. They can detect subtle alterations and pan-cardiac involvement, while also providing important insights into the complex underlying mechanisms of the syndrome.

Advanced Cardiovascular Magnetic Resonance Imaging in Takotsubo Syndrome: Update on Feature Tracking and Tissue Mapping / Sclafani, M.; Tini, G.; Musumeci, B.; Cianca, A.; Maestrini, V.; Cacciotti, L.; Arcari, L.. - In: CURRENT CARDIOVASCULAR IMAGING REPORTS. - ISSN 1941-9066. - 17:6(2024), pp. 61-71. [10.1007/s12410-024-09593-9]

Advanced Cardiovascular Magnetic Resonance Imaging in Takotsubo Syndrome: Update on Feature Tracking and Tissue Mapping

Sclafani M.
Primo
;
Tini G.
Secondo
;
Musumeci B.;Cianca A.;Maestrini V.;Arcari L.
Ultimo
2024

Abstract

Backgrounds: Takotsubo syndrome (TTS) is an intriguing clinical entity characterized by transient myocardial dysfunction. The precise pathophysiological mechanism of TTS is still unknown, but recent evidence suggests a central role of systemic inflammation associated with adrenergic discharge. Although initially considered benign, TTS has shown several potential short-term and long-term complications and adverse outcomes. To improve understanding and management, advanced cardiovascular magnetic resonance (CMR) techniques, such as feature tracking (FT) and parametric mapping, have gained attention. Purpose of Review: The purpose of this review is to summarize the current literature on the clinical applications of CMR-FT and mapping in TTS. Additionally, the most significant and recent findings will be discussed. Recent Findings: FT-CMR enables the parametric quantification of myocardial deformation, allowing a comprehensive evaluation of left ventricular, right ventricular, and atrial function. It provides an accurate definition of areas of myocardial dysfunction and potentially serves as a superior prognostic tool compared to ejection fraction. Tissue mapping techniques enable precise and comprehensive tissue characterization by quantifying areas of oedema, and myocardial fibrosis. Summary: FT-CMR and mapping techniques serve as valuable prognostic tools both in the acute and chronic phases of TTS. They can detect subtle alterations and pan-cardiac involvement, while also providing important insights into the complex underlying mechanisms of the syndrome.
2024
Cardiovascular Magnetic Resonance; Feature Tracking; Mapping; Takotsubo
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Advanced Cardiovascular Magnetic Resonance Imaging in Takotsubo Syndrome: Update on Feature Tracking and Tissue Mapping / Sclafani, M.; Tini, G.; Musumeci, B.; Cianca, A.; Maestrini, V.; Cacciotti, L.; Arcari, L.. - In: CURRENT CARDIOVASCULAR IMAGING REPORTS. - ISSN 1941-9066. - 17:6(2024), pp. 61-71. [10.1007/s12410-024-09593-9]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1712064
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact