Various controlled delivery systems (CDSs) have been developed to overcome the shortcomings of traditional drug formulations (tablets, capsules, syrups, ointments, etc.). Among innovative CDSs, hydrogels and liposomes have shown great promise for clinical applications thanks to their cost‐effectiveness, well‐known chemistry and synthetic feasibility, biodegradability, biocompatibility and responsiveness to external stimuli. To date, several liposomal‐ and hydrogel‐based products have been approved to treat cancer, as well as fungal and viral infections, hence the integration of liposomes into hydrogels has attracted increasing attention because of the benefit from both of them into a single platform, resulting in a multifunctional drug formulation, which is essential to develop efficient CDSs. This short review aims to present an updated report on the advancements of liposome–hydrogel systems for drug delivery purposes.
Liposome–Hydrogel Composites for Controlled Drug Delivery Applications / Binaymotlagh, Roya; HAJAREH HAGHIGHI, Farid; Chronopoulou, Laura; Palocci, Cleofe. - In: GELS. - ISSN 2310-2861. - 10:4(2024), pp. 1-26. [10.3390/gels10040284]
Liposome–Hydrogel Composites for Controlled Drug Delivery Applications
Roya Binaymotlagh
;Farid Hajareh Haghighi
;Laura Chronopoulou
;Cleofe Palocci
2024
Abstract
Various controlled delivery systems (CDSs) have been developed to overcome the shortcomings of traditional drug formulations (tablets, capsules, syrups, ointments, etc.). Among innovative CDSs, hydrogels and liposomes have shown great promise for clinical applications thanks to their cost‐effectiveness, well‐known chemistry and synthetic feasibility, biodegradability, biocompatibility and responsiveness to external stimuli. To date, several liposomal‐ and hydrogel‐based products have been approved to treat cancer, as well as fungal and viral infections, hence the integration of liposomes into hydrogels has attracted increasing attention because of the benefit from both of them into a single platform, resulting in a multifunctional drug formulation, which is essential to develop efficient CDSs. This short review aims to present an updated report on the advancements of liposome–hydrogel systems for drug delivery purposes.File | Dimensione | Formato | |
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Binaymotlagh_Liposome–Hydrogel_2024.pdf
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