Public health genomics (PHG) aims to integrate advances in genomic sciences into healthcare for the benefit of the general population. As in many countries, there are various research initiatives in this field in Italy, but a clear picture of the national research portfolio has never been sketched. Thus, we aimed to provide an overview of current PHG research projects at the national or international level by consultation with Italian institutional and academic experts. We included 68 PHG projects: the majority were international projects in which Italian researchers participated (n = 43), mainly funded by the European Commission, while the remainder were national initiatives (N = 25), mainly funded by central government. Funding varied considerably, from euro 50,000 to euro 80,803,177. Three main research themes were identified: governance (N = 20); precision medicine (PM; N = 46); and precision public health (N = 2). We found that research activities are preferentially aimed at the clinical application of PM, while other efforts deal with the governance of the complex translation of genomic innovation into clinical and public health practice. To align such activities with national and international priorities, the development of an updated research agenda for PHG is needed.

Public health genomics research in Italy. An overview of ongoing projects / Pitini, E.; Baccolini, V.; Isonne, C.; Maran, P.; Marzuillo, C.; Villari, P.; Galeone, D.; Vaia, F.. - In: FRONTIERS IN PUBLIC HEALTH. - ISSN 2296-2565. - 12:(2024), pp. 1-9. [10.3389/fpubh.2024.1343509]

Public health genomics research in Italy. An overview of ongoing projects

Baccolini V.;Isonne C.;Marzuillo C.;Villari P.;
2024

Abstract

Public health genomics (PHG) aims to integrate advances in genomic sciences into healthcare for the benefit of the general population. As in many countries, there are various research initiatives in this field in Italy, but a clear picture of the national research portfolio has never been sketched. Thus, we aimed to provide an overview of current PHG research projects at the national or international level by consultation with Italian institutional and academic experts. We included 68 PHG projects: the majority were international projects in which Italian researchers participated (n = 43), mainly funded by the European Commission, while the remainder were national initiatives (N = 25), mainly funded by central government. Funding varied considerably, from euro 50,000 to euro 80,803,177. Three main research themes were identified: governance (N = 20); precision medicine (PM; N = 46); and precision public health (N = 2). We found that research activities are preferentially aimed at the clinical application of PM, while other efforts deal with the governance of the complex translation of genomic innovation into clinical and public health practice. To align such activities with national and international priorities, the development of an updated research agenda for PHG is needed.
2024
italy; governance; precision medicine; precision public health; public health genomics; research
01 Pubblicazione su rivista::01a Articolo in rivista
Public health genomics research in Italy. An overview of ongoing projects / Pitini, E.; Baccolini, V.; Isonne, C.; Maran, P.; Marzuillo, C.; Villari, P.; Galeone, D.; Vaia, F.. - In: FRONTIERS IN PUBLIC HEALTH. - ISSN 2296-2565. - 12:(2024), pp. 1-9. [10.3389/fpubh.2024.1343509]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1706249
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