We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.

The 5th edition of the World Health Organization classification of Haematolymphoid tumours. Lymphoid neoplasms / Alaggio, Rita; Amador, Catalina; Anagnostopoulos, Ioannis; D Attygalle, Ayoma; Barreto de Oliveira Araujo, Iguaracyra; Berti, Emilio; Bhagat, Govind; Maria Borges, Anita; Boyer, Daniel; Calaminici, Mariarita; Chadburn, Amy; C Chan, John K; Cheuk, Wah; Chng, Wee-Joo; K Choi, John; Chuang, Shih-Sung; E Coupland, Sarah; Czader, Magdalena; S Dave, Sandeep; de Jong, Daphne; Du, Ming-Qing; S Elenitoba-Johnson, Kojo; Ferry, Judith; Geyer, Julia; Gratzinger, Dita; Guitart, Joan; Gujral, Sumeet; Harris, Marian; J Harrison, Christine; Hartmann, Sylvia; Hochhaus, Andreas; M Jansen, Patty; Karube, Kennosuke; Kempf, Werner; Khoury, Joseph; Kimura, Hiroshi; Klapper, Wolfram; E Kovach, Alexandra; Kumar, Shaji; J Lazar, Alexander; Lazzi, Stefano; Leoncini, Lorenzo; Leung, Nelson; Leventaki, Vasiliki; Li, Xiao-Qiu; S Lim, Megan; Liu, Wei-Ping; Louissaint Jr, Abner; Marcogliese, Andrea; Jeffrey Medeiros, L; Michal, Michael; N Miranda, Roberto; Mitteldorf, Christina; Montes-Moreno, Santiago; Morice, William; Nardi, Valentina; N Naresh, Kikkeri; Natkunam, Yasodha; Ng, Siok-Bian; Oschlies, Ilske; Ott, German; Parrens, Marie; Pulitzer, Melissa; Vincent Rajkumar, S; C Rawstron, Andrew; Rech, Karen; Rosenwald, Andreas; Said, Jonathan; Sarkozy, Clémentine; Sayed, Shahin; Saygin, Caner; Schuh, Anna; Sewell, William; Siebert, Reiner; R Sohani, Aliyah; Tooze, Reuben; Traverse-Glehen, Alexandra; Vega, Francisco; Vergier, Beatrice; D Wechalekar, Ashutosh; Wood, Brent; Xerri, Luc; Xiao, Wenbin. - In: LEUKEMIA. - ISSN 0887-6924. - 36:7(2022), pp. 1720-1748. [10.1038/s41375-022-01620-2]

The 5th edition of the World Health Organization classification of Haematolymphoid tumours. Lymphoid neoplasms

Rita Alaggio;
2022

Abstract

We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.
2022
WHO; lymphoma classification
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
The 5th edition of the World Health Organization classification of Haematolymphoid tumours. Lymphoid neoplasms / Alaggio, Rita; Amador, Catalina; Anagnostopoulos, Ioannis; D Attygalle, Ayoma; Barreto de Oliveira Araujo, Iguaracyra; Berti, Emilio; Bhagat, Govind; Maria Borges, Anita; Boyer, Daniel; Calaminici, Mariarita; Chadburn, Amy; C Chan, John K; Cheuk, Wah; Chng, Wee-Joo; K Choi, John; Chuang, Shih-Sung; E Coupland, Sarah; Czader, Magdalena; S Dave, Sandeep; de Jong, Daphne; Du, Ming-Qing; S Elenitoba-Johnson, Kojo; Ferry, Judith; Geyer, Julia; Gratzinger, Dita; Guitart, Joan; Gujral, Sumeet; Harris, Marian; J Harrison, Christine; Hartmann, Sylvia; Hochhaus, Andreas; M Jansen, Patty; Karube, Kennosuke; Kempf, Werner; Khoury, Joseph; Kimura, Hiroshi; Klapper, Wolfram; E Kovach, Alexandra; Kumar, Shaji; J Lazar, Alexander; Lazzi, Stefano; Leoncini, Lorenzo; Leung, Nelson; Leventaki, Vasiliki; Li, Xiao-Qiu; S Lim, Megan; Liu, Wei-Ping; Louissaint Jr, Abner; Marcogliese, Andrea; Jeffrey Medeiros, L; Michal, Michael; N Miranda, Roberto; Mitteldorf, Christina; Montes-Moreno, Santiago; Morice, William; Nardi, Valentina; N Naresh, Kikkeri; Natkunam, Yasodha; Ng, Siok-Bian; Oschlies, Ilske; Ott, German; Parrens, Marie; Pulitzer, Melissa; Vincent Rajkumar, S; C Rawstron, Andrew; Rech, Karen; Rosenwald, Andreas; Said, Jonathan; Sarkozy, Clémentine; Sayed, Shahin; Saygin, Caner; Schuh, Anna; Sewell, William; Siebert, Reiner; R Sohani, Aliyah; Tooze, Reuben; Traverse-Glehen, Alexandra; Vega, Francisco; Vergier, Beatrice; D Wechalekar, Ashutosh; Wood, Brent; Xerri, Luc; Xiao, Wenbin. - In: LEUKEMIA. - ISSN 0887-6924. - 36:7(2022), pp. 1720-1748. [10.1038/s41375-022-01620-2]
File allegati a questo prodotto
File Dimensione Formato  
Alaggio_WHO-class_2022.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 5.45 MB
Formato Adobe PDF
5.45 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1703865
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1828
  • ???jsp.display-item.citation.isi??? 1682
social impact