Biomedical applications utilizing nanosecond pulsed electric fields (nsPEF) have demonstrated their ability to induce membrane rearrangement and modulate signaling pathways in biological cells. Proposed advancement in this field involves the activation of liposomes, as smart drug delivery nanocarriers, with nsPEF stimulation. In this work, the authors provide a multiphysics numerical study on liposomes exposed to nsPEF, comparing 2D and 3D models, to fill the gap between simulations and experiments.
Modeling liposome electroporation by nsPEF. Towards realism / Caramazza, Laura; Paffi, Alessandra; Liberti, Micaela; Apollonio, Francesca. - (2023), pp. 136-138. (Intervento presentato al convegno 2023 IEEE MTT-S International Microwave Biomedical Conference, IMBioC tenutosi a Leuven; Belgium) [10.1109/imbioc56839.2023.10305103].
Modeling liposome electroporation by nsPEF. Towards realism
Caramazza, LauraPrimo
;Paffi, AlessandraSecondo
;Liberti, MicaelaPenultimo
;Apollonio, FrancescaUltimo
2023
Abstract
Biomedical applications utilizing nanosecond pulsed electric fields (nsPEF) have demonstrated their ability to induce membrane rearrangement and modulate signaling pathways in biological cells. Proposed advancement in this field involves the activation of liposomes, as smart drug delivery nanocarriers, with nsPEF stimulation. In this work, the authors provide a multiphysics numerical study on liposomes exposed to nsPEF, comparing 2D and 3D models, to fill the gap between simulations and experiments.| File | Dimensione | Formato | |
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Caramazza_Modeling Liposome_Electroporation_2023.pdf
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