The asymmetric synthesis of warfarin in microdroplets and thin films generated by an electrospray ionization (ESI) source is reported. This is one of the first examples of an enantioselective organocatalyzed reaction in electrosprayed confined volumes. The optimal conditions in terms of system setting were established for this reaction.
Stereoselectivity in electrosprayed confined volumes: asymmetric synthesis of warfarin by diamine organocatalysts in microdroplets and thin films / DE ANGELIS, Martina; Managò, Marta; Pepi, Federico; Salvitti, Chiara; Troiani, Anna; Villani, Claudio; Ciogli, Alessia. - In: RSC ADVANCES. - ISSN 2046-2069. - 14:3(2024), pp. 1576-1580. [10.1039/D3RA07975A]
Stereoselectivity in electrosprayed confined volumes: asymmetric synthesis of warfarin by diamine organocatalysts in microdroplets and thin films
Martina De Angelis;Federico Pepi;Chiara Salvitti;Anna Troiani;Claudio Villani;Alessia Ciogli
2024
Abstract
The asymmetric synthesis of warfarin in microdroplets and thin films generated by an electrospray ionization (ESI) source is reported. This is one of the first examples of an enantioselective organocatalyzed reaction in electrosprayed confined volumes. The optimal conditions in terms of system setting were established for this reaction.| File | Dimensione | Formato | |
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