Facial movements are crucial for social and emotional interaction and well-being. Reduced facial expressions (i.e., hypomimia) is a common feature in patients with Parkinson’s disease (PD) and previous studies linked this manifestation to both motor symptoms of the disease and altered emotion recognition and processing. Nevertheless, research on facial motor impairment in PD has been rather scarce and only a limited number of clinical evaluation tools are available, often suffering from poor validation processes and high inter- and intra-rater variability. In recent years, the availability of technology-enhanced quantification methods of facial movements, such as automated video analysis and machine learning application, led to increasing interest in studying hypomimia in PD. In this narrative review, we summarize the current knowledge on pathophysiological hypotheses at the basis of hypomimia in PD, with particular focus on the association between reduced facial expressions and emotional processing and analyze the current evaluation tools and management strategies for this symptom, as well as future research perspectives.

The Story behind the Mask: A Narrative Review on Hypomimia in Parkinson’s Disease / Bianchini, Edoardo; Rinaldi, Domiziana; Alborghetti, Marika; Simonelli, Marta; D’Audino, Flavia; Onelli, Camilla; Pegolo, Elena; Pontieri, Francesco E.. - In: BRAIN SCIENCES. - ISSN 2076-3425. - 14:1(2024). [10.3390/brainsci14010109]

The Story behind the Mask: A Narrative Review on Hypomimia in Parkinson’s Disease

Bianchini, Edoardo
Primo
;
Rinaldi, Domiziana;Alborghetti, Marika;Simonelli, Marta;Pontieri, Francesco E.
2024

Abstract

Facial movements are crucial for social and emotional interaction and well-being. Reduced facial expressions (i.e., hypomimia) is a common feature in patients with Parkinson’s disease (PD) and previous studies linked this manifestation to both motor symptoms of the disease and altered emotion recognition and processing. Nevertheless, research on facial motor impairment in PD has been rather scarce and only a limited number of clinical evaluation tools are available, often suffering from poor validation processes and high inter- and intra-rater variability. In recent years, the availability of technology-enhanced quantification methods of facial movements, such as automated video analysis and machine learning application, led to increasing interest in studying hypomimia in PD. In this narrative review, we summarize the current knowledge on pathophysiological hypotheses at the basis of hypomimia in PD, with particular focus on the association between reduced facial expressions and emotional processing and analyze the current evaluation tools and management strategies for this symptom, as well as future research perspectives.
2024
hypomimia; Parkinson’s disease; facial expressions; amimia; emotion recognition; face; facial bradykinesia
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
The Story behind the Mask: A Narrative Review on Hypomimia in Parkinson’s Disease / Bianchini, Edoardo; Rinaldi, Domiziana; Alborghetti, Marika; Simonelli, Marta; D’Audino, Flavia; Onelli, Camilla; Pegolo, Elena; Pontieri, Francesco E.. - In: BRAIN SCIENCES. - ISSN 2076-3425. - 14:1(2024). [10.3390/brainsci14010109]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1700495
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