Clinical treatments for osteochondral defects (OCD) are only palliative, therefore the development of novel tissue engineering (TE) approaches for the active repair of damaged cartilage-bone interfaces is of utmost importance. To date, the morphological and functional renewal of OCD remains an unsolved clinical challenge. Conventional 2D and 3D morphology of TE scaffolds is not yet able to reproduce the complex tissue architecture. Here, we aim to explore a novel surface technology tailored to the OCD patient, using a robotic 3D electrospinning platform (3DES) to design ad-hoc woven scaffolds that correspond to the diseased tissue surfaces.
Near Field Electrospinning Process Using a Multi-Axis Robot / D'Alessandro, S.; Pica, A.; Marinozzi, F.; Bini, F.; Cidonio, G.. - (2023). (Intervento presentato al convegno 8th National Congress of Bioengineering, GNB 2023 tenutosi a Padova).
Near Field Electrospinning Process Using a Multi-Axis Robot
D'Alessandro S.Primo
;Marinozzi F.;Bini F.Penultimo
;Cidonio G.
Ultimo
Conceptualization
2023
Abstract
Clinical treatments for osteochondral defects (OCD) are only palliative, therefore the development of novel tissue engineering (TE) approaches for the active repair of damaged cartilage-bone interfaces is of utmost importance. To date, the morphological and functional renewal of OCD remains an unsolved clinical challenge. Conventional 2D and 3D morphology of TE scaffolds is not yet able to reproduce the complex tissue architecture. Here, we aim to explore a novel surface technology tailored to the OCD patient, using a robotic 3D electrospinning platform (3DES) to design ad-hoc woven scaffolds that correspond to the diseased tissue surfaces.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
