Stroke physicians and neurointerventionists should keep in mind that a clot is a vital and rapidly changing tissue. The sooner IV rt-PA is administered and endovascular thrombectomy is performed after stroke onset, the higher is the chance to dissolve the large vessel occluding thrombus and the better will be the outcome. That is a non-“neuro-centric” but “clot-centric” view of the ischemic stroke therapeutic time window. Indeed, time is not only brain but it is also clot: time lost is clot resolution lost.
"Time lost is clot resolution lost": the neglected perspective of the therapeutic time window for ischemic stroke / De Michele, Manuela; Lorenzano, Svetlana; Bertuccini, Lucia; Iosi, Francesca; Toni, Danilo. - In: FRONTIERS IN NEUROLOGY. - ISSN 1664-2295. - 14:(2023), p. 1177609. [10.3389/fneur.2023.1177609]
"Time lost is clot resolution lost": the neglected perspective of the therapeutic time window for ischemic stroke
De Michele, Manuela;Lorenzano, Svetlana;Toni, Danilo
2023
Abstract
Stroke physicians and neurointerventionists should keep in mind that a clot is a vital and rapidly changing tissue. The sooner IV rt-PA is administered and endovascular thrombectomy is performed after stroke onset, the higher is the chance to dissolve the large vessel occluding thrombus and the better will be the outcome. That is a non-“neuro-centric” but “clot-centric” view of the ischemic stroke therapeutic time window. Indeed, time is not only brain but it is also clot: time lost is clot resolution lost.| File | Dimensione | Formato | |
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fneur-14-1177609.pdf
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Note: De Michele_“Time lost is clot resolution lost”_2023
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