The aim of this study is to assess and analyze the intratubular penetration of the intracanal medications nitrofurantoin (Nit), triple antibiotic paste (TAP), and calcium hydroxide (CH). Sixty freshly extracted single-rooted teeth were acquired and decoronated to a standard length of 15 mm. To prepare specimens up to size F3, rotary ProTaper instrumentation was employed. The prepared teeth were divided into three groups, each of which received one of the tested intracanal medicaments: Group I (calcium hydroxide), Group II (triple antibiotic paste), and Group III (nitrofurantoin). Using a size #30 Lentulo spiral, a freshly prepared therapeutic paste was placed into the canals, and the intracanal medicaments were allowed to set in the incubator at 100% humidity. The samples were subsequently sliced perpendicularly to their long axis using a precision saw and assessed under a scanning electron microscope to assess the depth of penetration of intracanal medicaments at the coronal, middle, and apical portions of the root canal dentin. The data were analyzed using one-way ANOVA and Tukey’s post hoc test. The statistical analysis revealed a significant difference between the experimental groups in the quantity and depth of sealer penetration (p < 0.05). In particular, as compared to the Nit group, both the CH and TAP groups had significantly smaller penetration areas (p < 0.05). In conclusion, this ongoing investigation indicates that nitrofurantoin penetrated dentinal tubules better than calcium hydroxide or triple antibiotic paste.

Scanning electron microscopy analysis of the intratubular radicular dentin penetration of calcium hydroxide, triple antibiotic paste, and nitrofurantoin / Khanvilkar, U.; Pawar, S.; Bandekar, S.; Dhok, V.; Arora, S.; Pawar, A. M.; Pagnoni, F.; Reda, R.; Testarelli, L.. - In: JOURNAL OF PERSONALIZED MEDICINE. - ISSN 2075-4426. - 13:11(2023). [10.3390/jpm13111554]

Scanning electron microscopy analysis of the intratubular radicular dentin penetration of calcium hydroxide, triple antibiotic paste, and nitrofurantoin

Reda R.
Penultimo
Conceptualization
;
Testarelli L.
Ultimo
Supervision
2023

Abstract

The aim of this study is to assess and analyze the intratubular penetration of the intracanal medications nitrofurantoin (Nit), triple antibiotic paste (TAP), and calcium hydroxide (CH). Sixty freshly extracted single-rooted teeth were acquired and decoronated to a standard length of 15 mm. To prepare specimens up to size F3, rotary ProTaper instrumentation was employed. The prepared teeth were divided into three groups, each of which received one of the tested intracanal medicaments: Group I (calcium hydroxide), Group II (triple antibiotic paste), and Group III (nitrofurantoin). Using a size #30 Lentulo spiral, a freshly prepared therapeutic paste was placed into the canals, and the intracanal medicaments were allowed to set in the incubator at 100% humidity. The samples were subsequently sliced perpendicularly to their long axis using a precision saw and assessed under a scanning electron microscope to assess the depth of penetration of intracanal medicaments at the coronal, middle, and apical portions of the root canal dentin. The data were analyzed using one-way ANOVA and Tukey’s post hoc test. The statistical analysis revealed a significant difference between the experimental groups in the quantity and depth of sealer penetration (p < 0.05). In particular, as compared to the Nit group, both the CH and TAP groups had significantly smaller penetration areas (p < 0.05). In conclusion, this ongoing investigation indicates that nitrofurantoin penetrated dentinal tubules better than calcium hydroxide or triple antibiotic paste.
2023
calcium hydroxide; intracanal medication; nitrofurantoin; radicular dentine penetration; scanning electron microscopy; triple antibiotic paste
01 Pubblicazione su rivista::01a Articolo in rivista
Scanning electron microscopy analysis of the intratubular radicular dentin penetration of calcium hydroxide, triple antibiotic paste, and nitrofurantoin / Khanvilkar, U.; Pawar, S.; Bandekar, S.; Dhok, V.; Arora, S.; Pawar, A. M.; Pagnoni, F.; Reda, R.; Testarelli, L.. - In: JOURNAL OF PERSONALIZED MEDICINE. - ISSN 2075-4426. - 13:11(2023). [10.3390/jpm13111554]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1694311
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