Aim: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery. Method: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien-Dindo III-V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement. Results: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48-5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61-1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67-2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91-1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87-2.99, p = 0.128). Conclusion: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery.

Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery. An international, prospective cohort study / Sgrò, A; Blanco-Colino, R; Ahmed, Wur; Brindl, N; R Gujjuri, R; Lapolla, P; C Mills, E; Pérez-Ajates, S; S Soares, A; Varghese, C; Xu, W; A McLean, K; J Chapman, S; Espín-Basany, E; C Glasbey, J; Mihaljevic, A; Nepogodiev, D; Pata, F; Pellino, G; Pockney, P; N Dudi-Venkata, N; Egoroff, N; Ludbrook, I; Raubenheimer, K; Richards, T; Pockney, P; Delibegovic, S; Salibasic, M; Amjad, T; Brindl, N; Dörr-Harim, C; Gedeon, N; Gsenger, J; Mihaljevic, A; Tachezy, M; Bini, S; Gallo, G; Gori, A; Lapolla, P; Pata, F; Pellino, G; Picciariello, A; Podda, M; Riboni, C; J Machatschek, M; Nguyen, A; Jakubauskas, M; Kryzauskas, M; Poskus, T; Z Kuiper, S; Wang, J; I Wells, C; P Bissett, I; M Augestad, K; Steinholt, I; S Soares, A; N Vieira, B; Juloski, J; Anabitarte Bautista, O; Kasmy El Kasmy, Y; Pérez-Ajates, S; Martín-Borregón, P; Ossola Revilla, M; Espín-Basany, E; Van Straten, S; K Aktas, M; E Baki, B; Ahmed, Wur; Akhbari, M; Baker, D; Bhatia, S; Brown, S; Cambridge, W; K Kamarajah, S; A Khaw, R; Kouli, O; A McLean, K; C Mills, E; Murray, V; Trout, I; Yasin, I; Y Wong, J; Reyhani, H; Wong, Khf; Pancharatnam, R; L Chia, W; Walmsley, A; Hassane, A; Saeed, D; Wang, B; Walters, B; Nowinka, Z; Alsaif, A; Mirza, M; Foster, K; Luu, J; Kakodkar, P; T Hughes, J; Yogarajah, T; Antypas, A; Rahman, A; Bradbury, M; Mclarnon, M; Nagi, S; M Riad, A; Erotocritou, M; Kyriacou, H; Kaminskaite, V; Alfadhel, S; Fatimah Hussain, Q; Handa, A; Massy-Westropp, C; Čustović, S; Dimov, R; Mughal, H; Slavchev, M; Ivanov, T; Gouvas, N; Hegazi, A; Kocián, P; D Kjaer, M; Mark-Christensen, A; Papakonstantinou, D; Machairas, N; Triantafyllou, T; Garoufalia, Z; Korkolis, D; Castaldi, A; Picciariello, A; Giaccari, S; Spolverato, G; Pagano, G; Milone, M; Turri, G; Colombo, F; Cucinotta, E; Poillucci, G; Lapolla, P; Bini, S; Perra, T; Tutino, R; Belia, F; Coletta, D; Belli, A; Rega, D; Cianci, P; Pirozzolo, G; Di Lena, M; Perrone, F; Giani, A; Lovisetto, F; Grassia, M; S Pipitone Federico, N; Ferrara, F; Biancafarina, A; Tamini, N; Sinibaldi, G; Tuminello, F; Galleano, R; Sasia, D; Bragaglia, L; de Manzoni Garberini, A; Pesce, A; Cassaro, F; Venturelli, P; Gori, A; L Canu, G; Esposito, G; Campanelli, M; Cardia, R; Ricciardiello, M; Sagnotta, A; Canonico, G; De Marco, G; Cappiello, A; Pinotti, E; Carlei, F; Lisi, G; Bagaglini, G; Gallo, G; Nguyen, A; J Machatschek, M; Farrugia, M; M Meima-van Praag, E; Monteiro, C; Pereira, M; Botelho, P; Quigley, A; O'Neill, A; Gaule, L; Crone, L; Arnold, A; Grama, F; Beuca, A; Tulina, I; Litvin, A; Juloski, J; Panyko, A; E Ossola, M; Trujillo Díaz, J; M Marín Santos, J; Alonso Batanero, E; Gortázar de Las Casas, S; Soldevila Verdeguer, C; Colás-Ruiz, E; Talal El-Abur, I; García Domínguez, M; Delorme, M; Sauvain, M; B Ozmen, B; K Aktas, M; B Ozkan, B; Calikoglu, F; Kural, S; Zafer, F; Kaya, Y; Yalcinkaya, A; Kargici, K; D Tepe, M; C Tatar, O; Kabadayi, E; Yıldırım, A; Hurmuzlu, D; Korkmaz, K; Sharma, P; Troller, R; Hagan, N; Mooney, J; Light, A; Tansey, M; Bhojwani, D; M McGing, R; Mallon, A; Fadel, M; Spilsbury, C; James, R; O'Brien, S; Isaac, A; Balasubramanya, S; Sadik, H; Gala, T; Y Chen, J; Turner, B; Goh, E; Hassan, K; Karam, M; Mason, P; Tzoumas, N; Noton, T; K Seehra, J; Ahmed, N; Motiwale, R; Tanna, V; Argyriou, A; K Bylapudi, S; Grace, N; Latif, S; Hounat, A; S Kiam, J; Zaidi, M; Elsamani, K; Hughes, C; Suresh, A; Sinan, Loh; El-Dalil, D; Khoo, Ejm; E Salim, E; Stark, D; Minhas, N; Fowler, G; Rees, E; Giudiceandrea, I; Bardon, A; Jayawardena, P; Dieseru, N; Murphy, A; Yates, C; Ziolkowska, K; Rafie, A; Khoda, F; Okocha, M; Ashdown, T; Vitish-Sharma, P; Gilliland, J; Toh, S; Jones, K; Devine, A; Berry, A; Mcdonnell, S; Olivier, J; Richardson, G; J Lim, H; Vitish-Sharma, P; Slim, N; Elsayeh, K; Sammour, T; Dimov, R; Sarpanov, A; Belev, N; Dimitrov, D; Gouvas, N; Dušek, T; Kocián, P; D Kjaer, M; Mark-Christensen, A; Ntomi, V; C Sotiropoulos, G; Theodorou, D; Nikiteas, N; Balalis, D; Antropoli, C; F Altomare, D; Luglio, G; D De Palma, G; Pedrazzani, C; Cucinotta, E; Simonelli, L; Brozzetti, S; Porcu, A; Massani, M; L Grazi, G; Izzo, F; Delrio, P; Restini, E; Pirozzolo, G; Chetta, G; Lantone, G; Ferrari, G; Lovisetto, F; Lucchi, A; De Prizio, M; Tamini, N; Sinibaldi, G; Galleano, R; Caristo, G; Borghi, F; Petrucciani, N; de Manzoni Garberini, A; Huscher, C; Cocorullo, G; Tonini, V; Medas, F; Podda, M; Sica, G; Cillara, N; Ricciardiello, M; Anastasi, A; De Marco, G; Bianco, F; Giuliani, A; Carlini, M; Selvaggi, F; Sammarco, G; Ozoliņš, A; Malašonoks, A; Andrejevic, P; Tanis, P; van de Ven, A; Gerhards, M; Ribeiro da Silva, B; Silva, A; J Lima, M; Kavanagh, D; Mccawley, N; Kavanagh, D; Grama, F; Bintintan, V; Karamarkovic, A; Panyko, A; Sanz Ortega, G; De Andrés-Asenjo, B; Nevado García, C; J García Flórez, L; J Segura-Sampedro, J; Colás-Ruiz, E; L Blas Laina, J; Ponchietti, L; Buchwald, P; Gialamas, E; Ozben, V; Rencuzogullari, A; E Gecim, İ; Altinel, Y; Isik, O; Yoldas, T; Isik, A; Leventoğlu, S; S Ertürk, M; Guner, A; A Güler, S; Attaallah, W; Ugur, M; S Özbalcı, G; Marzook, H; Eardley, N; Smolarek, S; Morgan, R; Roxburgh, C; K Lala, A; Salama, Y; Singh, B; Khanna, A; Evans, M; Shaikh, I; Maradi Thippeswamy, K; Appleton, B; Moug, S; Smith, I; Smart, N; Shah, P; Williams, G; Khera, G; Goede, A; Varcada, M; Parmar, C; Duff, S; Hargest, R; Marriott, P; Speake, D; Ben Sassi, A; Goede, A; Furfaro, B; Daudu, D; Golijanin, N; Y Yek, W; Capasso, G; T Mansour, L; Niu, N; Seow, W; Hamidovic, A; Kulovic, E; Letic, E; Aljić, A; Letic, E; Helez, M; Banji-Kelan, A; Dimitrova, N; Kavradjieva, P; Ivanov, V; Jukaku, A; Hadzhiev, D; Mughal, H; Slavchev, M; Gabarski, A; Karamanliev, M; Vladova, P; Iliev, S; Yotsov, T; Ευσταθίου, Η; Vetsa, K; Gouvas, N; Stavrinidou, O; Papatheodorou, P; Liassides, T; Georgiou, T; Hegazi, A; Al Nassrallah, M; Altaf, R; Amjad, T; Negametzyanov, M; Dušek, T; Zagibová, D; Foltys, F; Štefanová, H; Paspala, A; Papakonstantinou, D; Bompetsi, G; Sidiropoulos, T; C Sotiropoulos, G; Machairas, N; Stamopoulos, P; Triantafyllou, A; Theodoropoulos, C; Kimpizi, A; Theodorou, D; Triantafyllou, T; Palyvou, T; Charalabopoulos, A; Syllaios, A; Schizas, D; Liatsou, E; Baili, E; Vagios, I; Tomara, N; Davakis, S; Balalis, D; Palumbo, A; Castaldi, A; Foroni, F; Picciariello, A; F Altomare, D; Dibra, R; Papagni, V; Urbani, A; Rossin, E; Nezi, G; Romano, P; Amendola, A; Esposito, E; Manigrasso, M; Anoldo, P; Vertaldi, S; Gecchele, G; Turri, G; S Sabrina, Z; Guerci, C; Cammarata, F; Lamperti, Gmb; Zaffaroni, G; Benuzzi, L; Ferrario, L; Cigognini, M; Mazzeo, C; Badessi, G; Pintabona, G; Fassari, A; Mingoli, A; Cirillo, B; D'Alterio, C; Brachini, G; Tancredi, M; Zambon, M; Aulicino, M; Sapienza, P; Lapolla, P; Liberatore, P; Bini, S; M Scanu, A; F Feo, C; Perra, T; Iacomino, A; Massani, M; Pelizzo, P; Tutino, R; Rossi, S; A Vigna, S; Grossi, U; Grillo, V; Agnes, A; A Schena, C; Belia, F; Marincola, G; Oddi, A; Perotti, B; Coletta, D; Mario, V; Perri, P; Zazza, S; Aversano, A; Scala, D; Di Lauro, K; Leongito, M; Piccirillo, M; Patrone, R; Restini, E; Cianci, P; Capuzzolo, S; Vignotto, C; Pirozzolo, G; R Bao, Q; Ruta, Giuseppe; Angarano, E; Di Lena, M; Marino, F; Perrone, F; Pezzolla, F; Gigante, G; Magistro, C; Crippa, J; Maspero, M; Carnevali, P; Lovisetto, F; Trapani, R; Zonta, S; Agostinelli, L; Vittori, L; Romeo, L; Doria, E; Farnesi, F; Danna, R; Ferrara, F; Biancafarina, A; Andolfi, E; A Pellicano', G; Angelini, M; Scricciolo, M; Zanframundo, C; Ciulli, C; Ripamonti, L; Cigagna, L; Oldani, M; Tamini, N; Larcinese, A; Rossi, D; Picone, E; Crescentini, G; Tuminello, F; Caristo, G; Marano, A; Sasia, D; Migliore, M; C Giuffrida, M; Palagi, S; Testa, V; Borrello, A; Lucarini, A; Garofalo, E; Canali, G; Bragaglia, L; Orlandi, P; de Manzoni Garberini, A; Nervegna, F; Marchegiani, F; Damoli, I; Licata, A; Trovato, C; Cassaro, F; Alicata, F; Sardo, F; Milazzo, M; Randisi, B; M Dominici, D; Cocorullo, G; Venturelli, P; Gori, A; Sartarelli, L; Zanni, M; Pisanu, A; Soddu, C; Delogu, D; Erdas, E; Campus, F; Cappellacci, F; Casti, F; Esposito, G; Marcialis, J; Atzeni, J; G Podda, M; Sensi, B; Sica, G; Franceschilli, M; Campanelli, M; Bellato, V; Cannavera, A; Putzu, G; Cillara, N; F di Mola, F; Ricciardiello, M; Sagnotta, A; Picardi, B; Solinas, L; Loponte, M; Rossi Del Monte, S; Rossi, S; Di Martino, C; Linari, C; Spagni, G; Capezzuoli, L; Tirloni, L; Nelli, T; Caridi, A; Elter, C; Camassa, M; D'Amico, S; Bargellini, T; Cappiello, A; Bianco, F; Incollingo, P; Pinotti, E; Montuori, M; Maffione, F; Romano, L; Valiyeva, S; Spoletini, D; Lisi, G; Carlini, M; Menegon Tasselli, F; Pellino, G; Bagaglini, G; Sciaudone, G; Selvaggi, L; P Menna, M; De Paola, G; Sammarco, G; Fulginiti, S; Truskovs, A; Weiß, C; Saknītis, G; Rauscher, Jtr; Larnovskis, J; Jeyarajan-Davidsson, M; Malašonoks, A; Nitisa, D; J Machatschek, M; Gille, N; C Reiser, S; Farrugia, M; Roshan, Mhk; Andrejevic, P; Leseman, C; Tanis, P; van de Ven, A; Chen, J; S van Dalen, A; Top, C; Gerhards, M; Detering, R; Matos, C; Monteiro, C; Silva, C; Pinto, D; Mendes, J; Couto, J; Leite, M; Velez, C; Damasio Cotovio, M; M Cinza, A; Pereira, M; Pedroso de Lima, R; Botelho, P; Quigley, A; Boyle, E; W Yang, H; Banerjee, I; Rahmat, S; Afzal, Z; O'Neill, A; Reid, C; Dumitrascu, F; A Croyle, J; Gressmann, K; Cullen, N; Graham, A; Nasehi, A; Montano King, C; Gaule, L; Martin, B; Stokell, C; Crone, L; Sanderson, N; Farnan, R; Jassim, S; Arnold, A; Chan, B; Chua Vi Long, K; Kaka, N; Pandey, S; X Neo, W; Chitul, A; Bezede, C; Grama, F; Beuca, A; Cincilei, D; David, A; Blaga, M; N Blaga, S; Fagarasan, V; Tulina, I; Khetagurova, M; Rodimov, S; Kapustina, A; Mekhralyzade, A; Zabiyaka, M; Juloski, J; Janković, U; Cuk, V; Panyko, A; Hájska, M; Dubovský, M; Hrošová, M; Ferancikova, N; Camarero Rodríguez, E; Laguna Alcántara, F; Adarraga, J; Jezieniecki, C; Ruiz Soriano, M; Gómez Sanz, T; Suarez, A; Sánchez García, C; M Marín Santos, J; Alonso Batanero, E; Cifrian Canales, I; Llosa Pérez, J; Merayo, M; Urbieta, A; Gegúndez Simón, A; F Tone, J; Gazo Martínez, J; Vicario Bravo, M; Chavarrias, N; Gil Catalán, A; Oseira, A; Villalonga, B; Soldevila Verdeguer, C; Jeri, S; Colás-Ruiz, E; Perez Calvo, J; Nogués, A; Cros, B; Yánez, C; Talal El-Abur, I; L Blas Laina, J; Utrilla Fornals, A; Roldón Golet, M; García Domínguez, M; Colsa, P; Gimenez Maurel, T; Delorme, M; Buchwald, P; Axmarker, T; Gialamas, E; Chevallay, M; V Pham, T; B Ozmen, B; K Sel, E; Ozben, V; Atar, C; K Aktas, M; Aba, M; B Ozkan, B; Sarkin, M; M Akkaya, Y; G Durmaz, A; Calikoglu, F; F Gullu, H; Boğa, A; Aktaş, A; Bakar, B; T Demirel, M; Kural, S; Hysejni, X; Zafer, F; Taser, M; R Guzel, O; Bozbiyik, O; Isik, A; Özen, D; Ölmez, M; Kaya, Y; Uyar, B; Gülçek, E; S Kayacan, G; Atıcı, N; F Gul, O; Altiner, S; Ibis, B; Altunsu, S; Banaz, T; Diler, C; Demirbas, I; A Usta, M; Erkul, O; Orman, R; Salih, S; Z Utkan, N; C Tatar, O; A Güler, S; Acil, C; Ozgur, E; Maddahali, M; B Turhan, A; B Eskici, A; Ular, B; Doğru, M; U Öztürk, O; R Arslan, E; Panahi Sharif, A; Hurmuzlu, D; Dikmen, E; Ates, J; Bircan, R; Cavus, T; E Sever, A; Balak, B; Duman, E; Korkmaz, K; Altay, L; Emanet, O; Cullen, F; Y Tan, J; Sharma, P; Nathan, A; Rottenberg, A; Y Williams, C; G Mitrofan, C; Xu, D; H Bawa, J; Morris, P; Troller, R; Gordon, D; Richmond, G; C Hui, J; Hagan, N; Ighomereho, O; Rocks, R; Mccabe, S; Fitzpatrick, A; Mooney, J; Nicoletti, J; C Hui, J; Auterson, L; Darrah, N; Soh, Vwy; Light, A; S Ong, C; Utukuri, M; Gallagher, C; M Stuart, L; Hipolito, M; Douglas, N; Ghazal, R; Parris, G; Catchpole, J; Tansey, M; Bryden, M; Jamal, S; Karim, Z; Lyon-Dean, C; Bhojwani, D; Rowley, G; S Lee, K; Whitehurst, O; Mirza, A; Sheikh, F; Yousaf, H; Bilbao, J; Sinclair, R; Takar, S; Kressel, H; M McGing, R; Chan, V; Mallon, A; Schack, K; Osborne, R; Baldemor, S; Smyth, S; Gilmour, S; Ting, A; Bozonelou, I; Saunders, P; A Qhaireel Anwar, Q; Tirimanna, R; Jauhari, S; Gardener, A; Walker, B; Spilsbury, C; Wenban, C; Reddy, H; Conway-Jones, R; Loganathan, S; Clynch, A; James, C; Matey, E; Cameron, F; James, R; Roberts, W; Gicquel, A; Milliken, C; Forbes, J; Rubinchik, P; O'Brien, S; Isaac, A; Azmi, A; Hawkes, C; Cornett, L; Adarkwah, P; Mcconville, R; O'Hara, S; Tijare, C; Parkes, J; Yao, L; Ahmad, R; Balasubramanya, S; Shafiq, U; Mhaisalkar, A; Gurung, A; Sadik, H; de Stadler, K; Elias, S; Hunefeldt, Thomas; Madras, A; Jani, A; K Daler, H; S Tong, K; S Sundaralingam, S; Nowinka, Z; Szal, A; Khan, A; O'Sullivan, C; Baker, E; Joseph-Gubral, J; Gala, T; Y Chen, J; Turner, B; Hadley, E; Trivedi, R; Igwelaezoh, E; Goh, E; Barton, H; Allison, W; Hurst, W; Alam, F; Parkes, I; Hassan, K; Jamshaid, M; Azizan, N; Burgher, T; Afzal, A; Eltilib, I; Zahid, M; Sadiq, O; Lloyd, A; Mason, P; Ho, R; Brazukas, A; H Li, C; Kamdar, M; N Mohamed Nazeer, M; Tzoumas, N; Mighiu, A; Kim, D; Wilkins, L; Kuo, L; Conway-Jones, R; Rafe, T; Noton, T; Maduka, D; Cheema, H; Farag, K; Mirza, M; Abdellatif, M; Nzewi, R; Kruczynska, A; Grasselli, H; Yousuff, M; Ahmed, N; Bassi, R; K Mann, A; Chopra, J; Shaikh, M; Sharma, P; D Sa, S; Tsimplis, V; Ghanchi, A; Skene, E; Asim, K; Zaheer, M; Chan, S; Dalton, H; Gibbons, K; Adderley, O; Chukwujindu, I; Jayasuriya, I; Sivanu, K; Borumand, M; K Bylapudi, S; Chick, G; Bridges, I; Tomlin, J; Mckenna, J; Nandra, N; Grace, N; Grieco, C; F Quek, F; Mercer, R; Latif, S; Brankin-Frisby, T; Sattar, A; Aslam, A; Edelsten, E; Shafi, S; Kouli, T; Ford, V; Gurung, F; S Kiam, J; Fernandes, M; Deader, N; Ponniah, R; Jamieson, S; Davies, A; Taubwurcel, J; T Aung, M; Desai, R; Begum, S; Jamadar, T; Kangatharan, A; Rzeszowski, B; Ho, C; Yap, Shk; Prendergast, M; Sethi, R; Duku, A; Lowe, C; Bray, J; Elsamani, K; Ghobrial, M; Nichita, V; Wagstaff, A; Hughes, C; Rengasamy, E; Abu Hassan, F; Mahmood, H; Savill, N; Shah, S; Almeida, T; Sinan, Loh; Edwards, A; Antypas, A; Catchpole, B; El-Dalil, D; Halford, Z; Carmichael, A; Khoo, Ejm; Alsusa, H; E Salim, E; Boyd, M; Reid, C; Stark, D; Williams, J; Feyi-Waboso, J; Patel, M; Zeidan, Z; Bailey, E; Bapty, J; Brazkiewicz, M; Minhas, N; Tremlett, A; Fowler, G; Pringle, H; Mankal, S; Kaminskaite, V; Chung, W; Rees, E; Parry-Jones, E; Anderson, K; Mcforrester, A; Stanley, A; Hoather, A; Wise, H; Laid, I; Giudiceandrea, I; Scriven, J; Braniste, A; Wilson, A; Le Blevec, L; Pakunwanich, N; Evans, N; L Chong, H; White, C; Hunter, J; Haque, M; Vanalia, P; Murdoch, S; Choudhary, T; Mccann, A; Harun, A; Shah, H; Dieseru, N; Hunt, S; Shafiq, Y; Murphy, A; Bickley-Morris, E; Emms, L; Dare, M; Patel, M; Akula, Y; Yates, C; Deliyannis, E; Mayes, F; Ellacott, M; Zagorac, Z; Farren, A; Manning, C; Hughed, C; G Stewart, E; H Lim, K; Chohan, N; Thaker, A; Thompson, B; Ziolkowska, K; Ahari, D; Burdekin, E; Okwu, U; Akintunde, A; Lhaf, F; Khoda, F; Douthwaite, J; Govindan, R; Leelamanthep, S; Gull, E; Wright, F; Dundas, L; Okocha, M; Mackdermott, N; Burchi-Khairy, T; Campbell, I; Walsh, J; Y Yeo, J; Meehan, S; Banerjee, D; Fu, M; Kawka, M; Ali, T; Hussain, Z; Thomas, C; Ahmad, H; Moroney, J; Yick, C; Risquet, R; Ntuiabane, D; Shimato, M; Khan, M; Ilangovan, S; M Vaselli, N; Smithers, R; Uhanowita Marage, R; Valnarov-Boulter, A; Kayran, J; Banerjee, M; Parekh-Hill, N; Hooper, A; Bowen, J; Jagdish, R; Mcquoid, C; Khan, N; O Hare, R; Jeffery, S; Devine, A; Zahid, A; Elsworth, C; Walter, L; Dhillon, S; Rao, S; Anthony, A; Ashaye, A; Phillips, N; Faderani, R; Pengelly, S; Choi, S; Y Kwak, S; Lau, Yhl; Bagheri, K; Pancharatnam, R; Mcdonnell, S; Ong, Dyc; Kerr, E; Falconer, K; Clancy, N; Douglas, S; Zhang, Y; Greenfield, F; Mutanga, I; Mcalinden, J; Olivier, J; Willis, L; Adefolaju, A; Agarwal, H; Barter, R; Harris, G; Spencer, G; J Lim, H; W Lee, M; V Vadiveloo, T; Herbert, G; Moroney, J; Yick, C; Patel, R; Risquet, R; Shah, M; Slim, N; El Falaha, S; Wong, C; Soare, C; Akram, J; Elsayeh, K; Bozhkova, L; Ma, Y; G Vo, U; Tan, Hwn; Leto, L; A Kamal, M; Hadzhieva, E; Krastev, P; Tonchev, P; Kokkinos, G; Pozotou, I; Sabbagh, D; Votava, J; Kocián, P; St, F; Koliakos, N; Tsaparas, P; Zografos, G; Mantas, D; Tsourouflis, G; Fradelos, E; Castaldi, A; Trigiante, G; Labellarte, G; Resta, G; Capelli, G; D'Amore, A; Verlingieri, V; Campagnaro, T; Maffioli, A; Viscosi, F; De Lucia, C; Poillucci, G; Meneghini, S; Fancellu, A; Colella, M; Biondi, A; De Peppo, V; Pace, U; Albino, V; Gattulli, D; Piangerelli, A; Kalivaci, D; Sisto, G; Mazzola, M; Caneparo, A; Grassia, M; G Lunghi, E; Andolfi, E; C Nespoli, L; Angrisani, M; Sinibaldi, G; Langone, A; Galleano, R; Gelarda, E; Virgilio, E; Angelini, E; Fornasier, C; Asero, S; Venturelli, P; Filippone, E; Frongia, F; G Calò, P; Bellato, V; Panaccio, P; Sagnotta, A; Loponte, M; Ipponi, P; D'Amico, S; Gili, S; Giuliani, A; Lisi, G; Braccio, B; Tiesi, V; Stolcers, K; Kokaine, L; Novikovs, V; Farrugia, M; Capel, L; Bastiaenen, V; Heijmans, H; Ribeiro da Silva, B; Silva, A; Botelho, P; Henriques, S; Z Gan, S; Ramanayake, H; Nolan, M; Kakodkar, P; Temperley, H; Kakodkar, P; Ciofic, E; Beuca, A; A Pop, B; Kurtenkov, M; Jovanović, M; Vician, M; Egea Arias, P; Beltrán de Heredia, J; Labalde Martinez, M; De Santiago Alvarez, I; Alvarez-Gallego, M; Colás-Ruiz, E; Talal El-Abur, I; M Rodriguez Artigas, J; Dwidar, O; K Korkmaz, H; C Eray, I; Meriç, S; Aydin, R; Çetin, B; Özen, D; Yalcinkaya, A; E Karaca, B; F Kuyumcu, O; E Baki, B; Yüksel, E; K Uprak, T; Ugur, M; Karabulut, K; Kavukçu, E; Mansor, A; Troller, R; Hackett, R; Zammit-Maempel, M; Sabaratnam, R; Nicoletti, J; Maan, A; Ferarrio, I; Dixon, L; Halai, H; Sethi, S; Nelson, L; Grassam-Rowe, A; Krishnan, E; Deeny, D; Mckeever, M; George Pandeth, A; Dhavala, P; Sreenivasan, S; Sundaram Venkatesan, G; Zhu, L; Atiyah, Z; Gregory, J; Morey, T; Seymour, Z; Holdsworth, L; Abdelmahmoud, S; Bourhill, J; Bisheet, G; Shaw, J; Kulkarni, K; Kumarakulasingam, P; Pillay, S; Al-Habsi, R; Kungwengwe, G; Richards, J; Davoudi, K; Ibrahim, B; Tailor, B; Zayed, M; Chen, F; Bailey, S; Sheefat, S; Nawaz, G; Pawar, R; Marsh, S; H Sam, Z; Roy Bentley, S; Simpson, C; Hughes, J; Lim, Y; Ooi, R; H Toh, W; Mannion, P; Lovett, A; Kinčius, A; Hussein, S; Kirby, E; G Beckett, R; Salmon, J; Rafie, A; Glynn, T; Y Choo, S; Lyons, S; Browne, D; Ravindran, W; Ahmad, S; Erotocritou, M; Zhu, X; Erotocritou, M; Bradbury, M; Mcnulty, J; Mccarthy, L; Ng, J; Karmally, Z; Mcteir, K; Hanna, M; Tan, E; Namdeo, S; Schembri, R; Pusey, E. - In: COLORECTAL DISEASE. - ISSN 1463-1318. - 25:10(2023), pp. 2043-2053. [10.1111/codi.16737]

Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery. An international, prospective cohort study

Lapolla, P;Mingoli, A;Cirillo, B;Brachini, G;Zambon, M;Sapienza, P;Lucarini, A;
2023

Abstract

Aim: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery. Method: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien-Dindo III-V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement. Results: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48-5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61-1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67-2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91-1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87-2.99, p = 0.128). Conclusion: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery.
2023
drain; emergency colorectal surgery; postoperative outcomes
01 Pubblicazione su rivista::01a Articolo in rivista
Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery. An international, prospective cohort study / Sgrò, A; Blanco-Colino, R; Ahmed, Wur; Brindl, N; R Gujjuri, R; Lapolla, P; C Mills, E; Pérez-Ajates, S; S Soares, A; Varghese, C; Xu, W; A McLean, K; J Chapman, S; Espín-Basany, E; C Glasbey, J; Mihaljevic, A; Nepogodiev, D; Pata, F; Pellino, G; Pockney, P; N Dudi-Venkata, N; Egoroff, N; Ludbrook, I; Raubenheimer, K; Richards, T; Pockney, P; Delibegovic, S; Salibasic, M; Amjad, T; Brindl, N; Dörr-Harim, C; Gedeon, N; Gsenger, J; Mihaljevic, A; Tachezy, M; Bini, S; Gallo, G; Gori, A; Lapolla, P; Pata, F; Pellino, G; Picciariello, A; Podda, M; Riboni, C; J Machatschek, M; Nguyen, A; Jakubauskas, M; Kryzauskas, M; Poskus, T; Z Kuiper, S; Wang, J; I Wells, C; P Bissett, I; M Augestad, K; Steinholt, I; S Soares, A; N Vieira, B; Juloski, J; Anabitarte Bautista, O; Kasmy El Kasmy, Y; Pérez-Ajates, S; Martín-Borregón, P; Ossola Revilla, M; Espín-Basany, E; Van Straten, S; K Aktas, M; E Baki, B; Ahmed, Wur; Akhbari, M; Baker, D; Bhatia, S; Brown, S; Cambridge, W; K Kamarajah, S; A Khaw, R; Kouli, O; A McLean, K; C Mills, E; Murray, V; Trout, I; Yasin, I; Y Wong, J; Reyhani, H; Wong, Khf; Pancharatnam, R; L Chia, W; Walmsley, A; Hassane, A; Saeed, D; Wang, B; Walters, B; Nowinka, Z; Alsaif, A; Mirza, M; Foster, K; Luu, J; Kakodkar, P; T Hughes, J; Yogarajah, T; Antypas, A; Rahman, A; Bradbury, M; Mclarnon, M; Nagi, S; M Riad, A; Erotocritou, M; Kyriacou, H; Kaminskaite, V; Alfadhel, S; Fatimah Hussain, Q; Handa, A; Massy-Westropp, C; Čustović, S; Dimov, R; Mughal, H; Slavchev, M; Ivanov, T; Gouvas, N; Hegazi, A; Kocián, P; D Kjaer, M; Mark-Christensen, A; Papakonstantinou, D; Machairas, N; Triantafyllou, T; Garoufalia, Z; Korkolis, D; Castaldi, A; Picciariello, A; Giaccari, S; Spolverato, G; Pagano, G; Milone, M; Turri, G; Colombo, F; Cucinotta, E; Poillucci, G; Lapolla, P; Bini, S; Perra, T; Tutino, R; Belia, F; Coletta, D; Belli, A; Rega, D; Cianci, P; Pirozzolo, G; Di Lena, M; Perrone, F; Giani, A; Lovisetto, F; Grassia, M; S Pipitone Federico, N; Ferrara, F; Biancafarina, A; Tamini, N; Sinibaldi, G; Tuminello, F; Galleano, R; Sasia, D; Bragaglia, L; de Manzoni Garberini, A; Pesce, A; Cassaro, F; Venturelli, P; Gori, A; L Canu, G; Esposito, G; Campanelli, M; Cardia, R; Ricciardiello, M; Sagnotta, A; Canonico, G; De Marco, G; Cappiello, A; Pinotti, E; Carlei, F; Lisi, G; Bagaglini, G; Gallo, G; Nguyen, A; J Machatschek, M; Farrugia, M; M Meima-van Praag, E; Monteiro, C; Pereira, M; Botelho, P; Quigley, A; O'Neill, A; Gaule, L; Crone, L; Arnold, A; Grama, F; Beuca, A; Tulina, I; Litvin, A; Juloski, J; Panyko, A; E Ossola, M; Trujillo Díaz, J; M Marín Santos, J; Alonso Batanero, E; Gortázar de Las Casas, S; Soldevila Verdeguer, C; Colás-Ruiz, E; Talal El-Abur, I; García Domínguez, M; Delorme, M; Sauvain, M; B Ozmen, B; K Aktas, M; B Ozkan, B; Calikoglu, F; Kural, S; Zafer, F; Kaya, Y; Yalcinkaya, A; Kargici, K; D Tepe, M; C Tatar, O; Kabadayi, E; Yıldırım, A; Hurmuzlu, D; Korkmaz, K; Sharma, P; Troller, R; Hagan, N; Mooney, J; Light, A; Tansey, M; Bhojwani, D; M McGing, R; Mallon, A; Fadel, M; Spilsbury, C; James, R; O'Brien, S; Isaac, A; Balasubramanya, S; Sadik, H; Gala, T; Y Chen, J; Turner, B; Goh, E; Hassan, K; Karam, M; Mason, P; Tzoumas, N; Noton, T; K Seehra, J; Ahmed, N; Motiwale, R; Tanna, V; Argyriou, A; K Bylapudi, S; Grace, N; Latif, S; Hounat, A; S Kiam, J; Zaidi, M; Elsamani, K; Hughes, C; Suresh, A; Sinan, Loh; El-Dalil, D; Khoo, Ejm; E Salim, E; Stark, D; Minhas, N; Fowler, G; Rees, E; Giudiceandrea, I; Bardon, A; Jayawardena, P; Dieseru, N; Murphy, A; Yates, C; Ziolkowska, K; Rafie, A; Khoda, F; Okocha, M; Ashdown, T; Vitish-Sharma, P; Gilliland, J; Toh, S; Jones, K; Devine, A; Berry, A; Mcdonnell, S; Olivier, J; Richardson, G; J Lim, H; Vitish-Sharma, P; Slim, N; Elsayeh, K; Sammour, T; Dimov, R; Sarpanov, A; Belev, N; Dimitrov, D; Gouvas, N; Dušek, T; Kocián, P; D Kjaer, M; Mark-Christensen, A; Ntomi, V; C Sotiropoulos, G; Theodorou, D; Nikiteas, N; Balalis, D; Antropoli, C; F Altomare, D; Luglio, G; D De Palma, G; Pedrazzani, C; Cucinotta, E; Simonelli, L; Brozzetti, S; Porcu, A; Massani, M; L Grazi, G; Izzo, F; Delrio, P; Restini, E; Pirozzolo, G; Chetta, G; Lantone, G; Ferrari, G; Lovisetto, F; Lucchi, A; De Prizio, M; Tamini, N; Sinibaldi, G; Galleano, R; Caristo, G; Borghi, F; Petrucciani, N; de Manzoni Garberini, A; Huscher, C; Cocorullo, G; Tonini, V; Medas, F; Podda, M; Sica, G; Cillara, N; Ricciardiello, M; Anastasi, A; De Marco, G; Bianco, F; Giuliani, A; Carlini, M; Selvaggi, F; Sammarco, G; Ozoliņš, A; Malašonoks, A; Andrejevic, P; Tanis, P; van de Ven, A; Gerhards, M; Ribeiro da Silva, B; Silva, A; J Lima, M; Kavanagh, D; Mccawley, N; Kavanagh, D; Grama, F; Bintintan, V; Karamarkovic, A; Panyko, A; Sanz Ortega, G; De Andrés-Asenjo, B; Nevado García, C; J García Flórez, L; J Segura-Sampedro, J; Colás-Ruiz, E; L Blas Laina, J; Ponchietti, L; Buchwald, P; Gialamas, E; Ozben, V; Rencuzogullari, A; E Gecim, İ; Altinel, Y; Isik, O; Yoldas, T; Isik, A; Leventoğlu, S; S Ertürk, M; Guner, A; A Güler, S; Attaallah, W; Ugur, M; S Özbalcı, G; Marzook, H; Eardley, N; Smolarek, S; Morgan, R; Roxburgh, C; K Lala, A; Salama, Y; Singh, B; Khanna, A; Evans, M; Shaikh, I; Maradi Thippeswamy, K; Appleton, B; Moug, S; Smith, I; Smart, N; Shah, P; Williams, G; Khera, G; Goede, A; Varcada, M; Parmar, C; Duff, S; Hargest, R; Marriott, P; Speake, D; Ben Sassi, A; Goede, A; Furfaro, B; Daudu, D; Golijanin, N; Y Yek, W; Capasso, G; T Mansour, L; Niu, N; Seow, W; Hamidovic, A; Kulovic, E; Letic, E; Aljić, A; Letic, E; Helez, M; Banji-Kelan, A; Dimitrova, N; Kavradjieva, P; Ivanov, V; Jukaku, A; Hadzhiev, D; Mughal, H; Slavchev, M; Gabarski, A; Karamanliev, M; Vladova, P; Iliev, S; Yotsov, T; Ευσταθίου, Η; Vetsa, K; Gouvas, N; Stavrinidou, O; Papatheodorou, P; Liassides, T; Georgiou, T; Hegazi, A; Al Nassrallah, M; Altaf, R; Amjad, T; Negametzyanov, M; Dušek, T; Zagibová, D; Foltys, F; Štefanová, H; Paspala, A; Papakonstantinou, D; Bompetsi, G; Sidiropoulos, T; C Sotiropoulos, G; Machairas, N; Stamopoulos, P; Triantafyllou, A; Theodoropoulos, C; Kimpizi, A; Theodorou, D; Triantafyllou, T; Palyvou, T; Charalabopoulos, A; Syllaios, A; Schizas, D; Liatsou, E; Baili, E; Vagios, I; Tomara, N; Davakis, S; Balalis, D; Palumbo, A; Castaldi, A; Foroni, F; Picciariello, A; F Altomare, D; Dibra, R; Papagni, V; Urbani, A; Rossin, E; Nezi, G; Romano, P; Amendola, A; Esposito, E; Manigrasso, M; Anoldo, P; Vertaldi, S; Gecchele, G; Turri, G; S Sabrina, Z; Guerci, C; Cammarata, F; Lamperti, Gmb; Zaffaroni, G; Benuzzi, L; Ferrario, L; Cigognini, M; Mazzeo, C; Badessi, G; Pintabona, G; Fassari, A; Mingoli, A; Cirillo, B; D'Alterio, C; Brachini, G; Tancredi, M; Zambon, M; Aulicino, M; Sapienza, P; Lapolla, P; Liberatore, P; Bini, S; M Scanu, A; F Feo, C; Perra, T; Iacomino, A; Massani, M; Pelizzo, P; Tutino, R; Rossi, S; A Vigna, S; Grossi, U; Grillo, V; Agnes, A; A Schena, C; Belia, F; Marincola, G; Oddi, A; Perotti, B; Coletta, D; Mario, V; Perri, P; Zazza, S; Aversano, A; Scala, D; Di Lauro, K; Leongito, M; Piccirillo, M; Patrone, R; Restini, E; Cianci, P; Capuzzolo, S; Vignotto, C; Pirozzolo, G; R Bao, Q; Ruta, Giuseppe; Angarano, E; Di Lena, M; Marino, F; Perrone, F; Pezzolla, F; Gigante, G; Magistro, C; Crippa, J; Maspero, M; Carnevali, P; Lovisetto, F; Trapani, R; Zonta, S; Agostinelli, L; Vittori, L; Romeo, L; Doria, E; Farnesi, F; Danna, R; Ferrara, F; Biancafarina, A; Andolfi, E; A Pellicano', G; Angelini, M; Scricciolo, M; Zanframundo, C; Ciulli, C; Ripamonti, L; Cigagna, L; Oldani, M; Tamini, N; Larcinese, A; Rossi, D; Picone, E; Crescentini, G; Tuminello, F; Caristo, G; Marano, A; Sasia, D; Migliore, M; C Giuffrida, M; Palagi, S; Testa, V; Borrello, A; Lucarini, A; Garofalo, E; Canali, G; Bragaglia, L; Orlandi, P; de Manzoni Garberini, A; Nervegna, F; Marchegiani, F; Damoli, I; Licata, A; Trovato, C; Cassaro, F; Alicata, F; Sardo, F; Milazzo, M; Randisi, B; M Dominici, D; Cocorullo, G; Venturelli, P; Gori, A; Sartarelli, L; Zanni, M; Pisanu, A; Soddu, C; Delogu, D; Erdas, E; Campus, F; Cappellacci, F; Casti, F; Esposito, G; Marcialis, J; Atzeni, J; G Podda, M; Sensi, B; Sica, G; Franceschilli, M; Campanelli, M; Bellato, V; Cannavera, A; Putzu, G; Cillara, N; F di Mola, F; Ricciardiello, M; Sagnotta, A; Picardi, B; Solinas, L; Loponte, M; Rossi Del Monte, S; Rossi, S; Di Martino, C; Linari, C; Spagni, G; Capezzuoli, L; Tirloni, L; Nelli, T; Caridi, A; Elter, C; Camassa, M; D'Amico, S; Bargellini, T; Cappiello, A; Bianco, F; Incollingo, P; Pinotti, E; Montuori, M; Maffione, F; Romano, L; Valiyeva, S; Spoletini, D; Lisi, G; Carlini, M; Menegon Tasselli, F; Pellino, G; Bagaglini, G; Sciaudone, G; Selvaggi, L; P Menna, M; De Paola, G; Sammarco, G; Fulginiti, S; Truskovs, A; Weiß, C; Saknītis, G; Rauscher, Jtr; Larnovskis, J; Jeyarajan-Davidsson, M; Malašonoks, A; Nitisa, D; J Machatschek, M; Gille, N; C Reiser, S; Farrugia, M; Roshan, Mhk; Andrejevic, P; Leseman, C; Tanis, P; van de Ven, A; Chen, J; S van Dalen, A; Top, C; Gerhards, M; Detering, R; Matos, C; Monteiro, C; Silva, C; Pinto, D; Mendes, J; Couto, J; Leite, M; Velez, C; Damasio Cotovio, M; M Cinza, A; Pereira, M; Pedroso de Lima, R; Botelho, P; Quigley, A; Boyle, E; W Yang, H; Banerjee, I; Rahmat, S; Afzal, Z; O'Neill, A; Reid, C; Dumitrascu, F; A Croyle, J; Gressmann, K; Cullen, N; Graham, A; Nasehi, A; Montano King, C; Gaule, L; Martin, B; Stokell, C; Crone, L; Sanderson, N; Farnan, R; Jassim, S; Arnold, A; Chan, B; Chua Vi Long, K; Kaka, N; Pandey, S; X Neo, W; Chitul, A; Bezede, C; Grama, F; Beuca, A; Cincilei, D; David, A; Blaga, M; N Blaga, S; Fagarasan, V; Tulina, I; Khetagurova, M; Rodimov, S; Kapustina, A; Mekhralyzade, A; Zabiyaka, M; Juloski, J; Janković, U; Cuk, V; Panyko, A; Hájska, M; Dubovský, M; Hrošová, M; Ferancikova, N; Camarero Rodríguez, E; Laguna Alcántara, F; Adarraga, J; Jezieniecki, C; Ruiz Soriano, M; Gómez Sanz, T; Suarez, A; Sánchez García, C; M Marín Santos, J; Alonso Batanero, E; Cifrian Canales, I; Llosa Pérez, J; Merayo, M; Urbieta, A; Gegúndez Simón, A; F Tone, J; Gazo Martínez, J; Vicario Bravo, M; Chavarrias, N; Gil Catalán, A; Oseira, A; Villalonga, B; Soldevila Verdeguer, C; Jeri, S; Colás-Ruiz, E; Perez Calvo, J; Nogués, A; Cros, B; Yánez, C; Talal El-Abur, I; L Blas Laina, J; Utrilla Fornals, A; Roldón Golet, M; García Domínguez, M; Colsa, P; Gimenez Maurel, T; Delorme, M; Buchwald, P; Axmarker, T; Gialamas, E; Chevallay, M; V Pham, T; B Ozmen, B; K Sel, E; Ozben, V; Atar, C; K Aktas, M; Aba, M; B Ozkan, B; Sarkin, M; M Akkaya, Y; G Durmaz, A; Calikoglu, F; F Gullu, H; Boğa, A; Aktaş, A; Bakar, B; T Demirel, M; Kural, S; Hysejni, X; Zafer, F; Taser, M; R Guzel, O; Bozbiyik, O; Isik, A; Özen, D; Ölmez, M; Kaya, Y; Uyar, B; Gülçek, E; S Kayacan, G; Atıcı, N; F Gul, O; Altiner, S; Ibis, B; Altunsu, S; Banaz, T; Diler, C; Demirbas, I; A Usta, M; Erkul, O; Orman, R; Salih, S; Z Utkan, N; C Tatar, O; A Güler, S; Acil, C; Ozgur, E; Maddahali, M; B Turhan, A; B Eskici, A; Ular, B; Doğru, M; U Öztürk, O; R Arslan, E; Panahi Sharif, A; Hurmuzlu, D; Dikmen, E; Ates, J; Bircan, R; Cavus, T; E Sever, A; Balak, B; Duman, E; Korkmaz, K; Altay, L; Emanet, O; Cullen, F; Y Tan, J; Sharma, P; Nathan, A; Rottenberg, A; Y Williams, C; G Mitrofan, C; Xu, D; H Bawa, J; Morris, P; Troller, R; Gordon, D; Richmond, G; C Hui, J; Hagan, N; Ighomereho, O; Rocks, R; Mccabe, S; Fitzpatrick, A; Mooney, J; Nicoletti, J; C Hui, J; Auterson, L; Darrah, N; Soh, Vwy; Light, A; S Ong, C; Utukuri, M; Gallagher, C; M Stuart, L; Hipolito, M; Douglas, N; Ghazal, R; Parris, G; Catchpole, J; Tansey, M; Bryden, M; Jamal, S; Karim, Z; Lyon-Dean, C; Bhojwani, D; Rowley, G; S Lee, K; Whitehurst, O; Mirza, A; Sheikh, F; Yousaf, H; Bilbao, J; Sinclair, R; Takar, S; Kressel, H; M McGing, R; Chan, V; Mallon, A; Schack, K; Osborne, R; Baldemor, S; Smyth, S; Gilmour, S; Ting, A; Bozonelou, I; Saunders, P; A Qhaireel Anwar, Q; Tirimanna, R; Jauhari, S; Gardener, A; Walker, B; Spilsbury, C; Wenban, C; Reddy, H; Conway-Jones, R; Loganathan, S; Clynch, A; James, C; Matey, E; Cameron, F; James, R; Roberts, W; Gicquel, A; Milliken, C; Forbes, J; Rubinchik, P; O'Brien, S; Isaac, A; Azmi, A; Hawkes, C; Cornett, L; Adarkwah, P; Mcconville, R; O'Hara, S; Tijare, C; Parkes, J; Yao, L; Ahmad, R; Balasubramanya, S; Shafiq, U; Mhaisalkar, A; Gurung, A; Sadik, H; de Stadler, K; Elias, S; Hunefeldt, Thomas; Madras, A; Jani, A; K Daler, H; S Tong, K; S Sundaralingam, S; Nowinka, Z; Szal, A; Khan, A; O'Sullivan, C; Baker, E; Joseph-Gubral, J; Gala, T; Y Chen, J; Turner, B; Hadley, E; Trivedi, R; Igwelaezoh, E; Goh, E; Barton, H; Allison, W; Hurst, W; Alam, F; Parkes, I; Hassan, K; Jamshaid, M; Azizan, N; Burgher, T; Afzal, A; Eltilib, I; Zahid, M; Sadiq, O; Lloyd, A; Mason, P; Ho, R; Brazukas, A; H Li, C; Kamdar, M; N Mohamed Nazeer, M; Tzoumas, N; Mighiu, A; Kim, D; Wilkins, L; Kuo, L; Conway-Jones, R; Rafe, T; Noton, T; Maduka, D; Cheema, H; Farag, K; Mirza, M; Abdellatif, M; Nzewi, R; Kruczynska, A; Grasselli, H; Yousuff, M; Ahmed, N; Bassi, R; K Mann, A; Chopra, J; Shaikh, M; Sharma, P; D Sa, S; Tsimplis, V; Ghanchi, A; Skene, E; Asim, K; Zaheer, M; Chan, S; Dalton, H; Gibbons, K; Adderley, O; Chukwujindu, I; Jayasuriya, I; Sivanu, K; Borumand, M; K Bylapudi, S; Chick, G; Bridges, I; Tomlin, J; Mckenna, J; Nandra, N; Grace, N; Grieco, C; F Quek, F; Mercer, R; Latif, S; Brankin-Frisby, T; Sattar, A; Aslam, A; Edelsten, E; Shafi, S; Kouli, T; Ford, V; Gurung, F; S Kiam, J; Fernandes, M; Deader, N; Ponniah, R; Jamieson, S; Davies, A; Taubwurcel, J; T Aung, M; Desai, R; Begum, S; Jamadar, T; Kangatharan, A; Rzeszowski, B; Ho, C; Yap, Shk; Prendergast, M; Sethi, R; Duku, A; Lowe, C; Bray, J; Elsamani, K; Ghobrial, M; Nichita, V; Wagstaff, A; Hughes, C; Rengasamy, E; Abu Hassan, F; Mahmood, H; Savill, N; Shah, S; Almeida, T; Sinan, Loh; Edwards, A; Antypas, A; Catchpole, B; El-Dalil, D; Halford, Z; Carmichael, A; Khoo, Ejm; Alsusa, H; E Salim, E; Boyd, M; Reid, C; Stark, D; Williams, J; Feyi-Waboso, J; Patel, M; Zeidan, Z; Bailey, E; Bapty, J; Brazkiewicz, M; Minhas, N; Tremlett, A; Fowler, G; Pringle, H; Mankal, S; Kaminskaite, V; Chung, W; Rees, E; Parry-Jones, E; Anderson, K; Mcforrester, A; Stanley, A; Hoather, A; Wise, H; Laid, I; Giudiceandrea, I; Scriven, J; Braniste, A; Wilson, A; Le Blevec, L; Pakunwanich, N; Evans, N; L Chong, H; White, C; Hunter, J; Haque, M; Vanalia, P; Murdoch, S; Choudhary, T; Mccann, A; Harun, A; Shah, H; Dieseru, N; Hunt, S; Shafiq, Y; Murphy, A; Bickley-Morris, E; Emms, L; Dare, M; Patel, M; Akula, Y; Yates, C; Deliyannis, E; Mayes, F; Ellacott, M; Zagorac, Z; Farren, A; Manning, C; Hughed, C; G Stewart, E; H Lim, K; Chohan, N; Thaker, A; Thompson, B; Ziolkowska, K; Ahari, D; Burdekin, E; Okwu, U; Akintunde, A; Lhaf, F; Khoda, F; Douthwaite, J; Govindan, R; Leelamanthep, S; Gull, E; Wright, F; Dundas, L; Okocha, M; Mackdermott, N; Burchi-Khairy, T; Campbell, I; Walsh, J; Y Yeo, J; Meehan, S; Banerjee, D; Fu, M; Kawka, M; Ali, T; Hussain, Z; Thomas, C; Ahmad, H; Moroney, J; Yick, C; Risquet, R; Ntuiabane, D; Shimato, M; Khan, M; Ilangovan, S; M Vaselli, N; Smithers, R; Uhanowita Marage, R; Valnarov-Boulter, A; Kayran, J; Banerjee, M; Parekh-Hill, N; Hooper, A; Bowen, J; Jagdish, R; Mcquoid, C; Khan, N; O Hare, R; Jeffery, S; Devine, A; Zahid, A; Elsworth, C; Walter, L; Dhillon, S; Rao, S; Anthony, A; Ashaye, A; Phillips, N; Faderani, R; Pengelly, S; Choi, S; Y Kwak, S; Lau, Yhl; Bagheri, K; Pancharatnam, R; Mcdonnell, S; Ong, Dyc; Kerr, E; Falconer, K; Clancy, N; Douglas, S; Zhang, Y; Greenfield, F; Mutanga, I; Mcalinden, J; Olivier, J; Willis, L; Adefolaju, A; Agarwal, H; Barter, R; Harris, G; Spencer, G; J Lim, H; W Lee, M; V Vadiveloo, T; Herbert, G; Moroney, J; Yick, C; Patel, R; Risquet, R; Shah, M; Slim, N; El Falaha, S; Wong, C; Soare, C; Akram, J; Elsayeh, K; Bozhkova, L; Ma, Y; G Vo, U; Tan, Hwn; Leto, L; A Kamal, M; Hadzhieva, E; Krastev, P; Tonchev, P; Kokkinos, G; Pozotou, I; Sabbagh, D; Votava, J; Kocián, P; St, F; Koliakos, N; Tsaparas, P; Zografos, G; Mantas, D; Tsourouflis, G; Fradelos, E; Castaldi, A; Trigiante, G; Labellarte, G; Resta, G; Capelli, G; D'Amore, A; Verlingieri, V; Campagnaro, T; Maffioli, A; Viscosi, F; De Lucia, C; Poillucci, G; Meneghini, S; Fancellu, A; Colella, M; Biondi, A; De Peppo, V; Pace, U; Albino, V; Gattulli, D; Piangerelli, A; Kalivaci, D; Sisto, G; Mazzola, M; Caneparo, A; Grassia, M; G Lunghi, E; Andolfi, E; C Nespoli, L; Angrisani, M; Sinibaldi, G; Langone, A; Galleano, R; Gelarda, E; Virgilio, E; Angelini, E; Fornasier, C; Asero, S; Venturelli, P; Filippone, E; Frongia, F; G Calò, P; Bellato, V; Panaccio, P; Sagnotta, A; Loponte, M; Ipponi, P; D'Amico, S; Gili, S; Giuliani, A; Lisi, G; Braccio, B; Tiesi, V; Stolcers, K; Kokaine, L; Novikovs, V; Farrugia, M; Capel, L; Bastiaenen, V; Heijmans, H; Ribeiro da Silva, B; Silva, A; Botelho, P; Henriques, S; Z Gan, S; Ramanayake, H; Nolan, M; Kakodkar, P; Temperley, H; Kakodkar, P; Ciofic, E; Beuca, A; A Pop, B; Kurtenkov, M; Jovanović, M; Vician, M; Egea Arias, P; Beltrán de Heredia, J; Labalde Martinez, M; De Santiago Alvarez, I; Alvarez-Gallego, M; Colás-Ruiz, E; Talal El-Abur, I; M Rodriguez Artigas, J; Dwidar, O; K Korkmaz, H; C Eray, I; Meriç, S; Aydin, R; Çetin, B; Özen, D; Yalcinkaya, A; E Karaca, B; F Kuyumcu, O; E Baki, B; Yüksel, E; K Uprak, T; Ugur, M; Karabulut, K; Kavukçu, E; Mansor, A; Troller, R; Hackett, R; Zammit-Maempel, M; Sabaratnam, R; Nicoletti, J; Maan, A; Ferarrio, I; Dixon, L; Halai, H; Sethi, S; Nelson, L; Grassam-Rowe, A; Krishnan, E; Deeny, D; Mckeever, M; George Pandeth, A; Dhavala, P; Sreenivasan, S; Sundaram Venkatesan, G; Zhu, L; Atiyah, Z; Gregory, J; Morey, T; Seymour, Z; Holdsworth, L; Abdelmahmoud, S; Bourhill, J; Bisheet, G; Shaw, J; Kulkarni, K; Kumarakulasingam, P; Pillay, S; Al-Habsi, R; Kungwengwe, G; Richards, J; Davoudi, K; Ibrahim, B; Tailor, B; Zayed, M; Chen, F; Bailey, S; Sheefat, S; Nawaz, G; Pawar, R; Marsh, S; H Sam, Z; Roy Bentley, S; Simpson, C; Hughes, J; Lim, Y; Ooi, R; H Toh, W; Mannion, P; Lovett, A; Kinčius, A; Hussein, S; Kirby, E; G Beckett, R; Salmon, J; Rafie, A; Glynn, T; Y Choo, S; Lyons, S; Browne, D; Ravindran, W; Ahmad, S; Erotocritou, M; Zhu, X; Erotocritou, M; Bradbury, M; Mcnulty, J; Mccarthy, L; Ng, J; Karmally, Z; Mcteir, K; Hanna, M; Tan, E; Namdeo, S; Schembri, R; Pusey, E. - In: COLORECTAL DISEASE. - ISSN 1463-1318. - 25:10(2023), pp. 2043-2053. [10.1111/codi.16737]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1693889
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact