Laboratory workers are exposed to the risk of acquiring infections due to the manipulation of infectious materials. The biological hazard for researchers is seven times higher when compared with hospital and public health laboratory workers. Despite the implementation of standardized practices to control infections, multiple cases of Laboratory Associated Infections (LAIs) usually go unreported. There has been a lack of comprehensive epidemiological data regarding the situation of LAIs for parasitic zoonosis and besides, the available sources are not completely updated. Since most accounts of laboratory infections are organism-specific, this study has focused on common pathogenic/zoonotic species handled at parasitological laboratories and summarising the standard biosecurity protocols for the infectious agents. The main characteristics of Cryptosporidium spp., Entamoeba spp, Giardia duodenalis, Toxoplasma gondii, Leishmania spp., Echinococcus spp., Schistosoma spp., Toxocara canis, Ancylostoma caninum, Strongyloides stercoralis are considered in this review in order to assess the potential risk of developing occupational infections in the workplace along with stating prevention and prophylactic measures for each species. It was concluded that the LAIs from these agents can be prevented by using personal protective measures and good laboratory practices. However, further studies are necessary to better understand the environmental resistance of cysts, oocysts and eggs, with a view to select the most suitable disinfection methods. Furthermore, it is fundamental to constantly update epidemiological data of infection acquired by laboratory workers, to develop accurate risk indicators.

Laboratory associated zoonotic parasitic infections. A review of main agents and biosecurity measures / Sini, Maria Francesca; Tamponi, Claudia; Mehmood, Naunain; Dessì, Giorgia; Ariu, Federica; Carta, Carlo; Coghetto, Alberto; Pentcheva, Plamena; Gabrielli, Simona; Scala, Antonio; Varcasia, Antonio. - In: JOURNAL OF INFECTION IN DEVELOPING COUNTRIES. - ISSN 1972-2680. - 17:6(2023), pp. 762-781. [10.3855/jidc.9428]

Laboratory associated zoonotic parasitic infections. A review of main agents and biosecurity measures

Gabrielli, Simona;
2023

Abstract

Laboratory workers are exposed to the risk of acquiring infections due to the manipulation of infectious materials. The biological hazard for researchers is seven times higher when compared with hospital and public health laboratory workers. Despite the implementation of standardized practices to control infections, multiple cases of Laboratory Associated Infections (LAIs) usually go unreported. There has been a lack of comprehensive epidemiological data regarding the situation of LAIs for parasitic zoonosis and besides, the available sources are not completely updated. Since most accounts of laboratory infections are organism-specific, this study has focused on common pathogenic/zoonotic species handled at parasitological laboratories and summarising the standard biosecurity protocols for the infectious agents. The main characteristics of Cryptosporidium spp., Entamoeba spp, Giardia duodenalis, Toxoplasma gondii, Leishmania spp., Echinococcus spp., Schistosoma spp., Toxocara canis, Ancylostoma caninum, Strongyloides stercoralis are considered in this review in order to assess the potential risk of developing occupational infections in the workplace along with stating prevention and prophylactic measures for each species. It was concluded that the LAIs from these agents can be prevented by using personal protective measures and good laboratory practices. However, further studies are necessary to better understand the environmental resistance of cysts, oocysts and eggs, with a view to select the most suitable disinfection methods. Furthermore, it is fundamental to constantly update epidemiological data of infection acquired by laboratory workers, to develop accurate risk indicators.
2023
biohazard; infection; parasite; prophylaxis; resistance; risk
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Laboratory associated zoonotic parasitic infections. A review of main agents and biosecurity measures / Sini, Maria Francesca; Tamponi, Claudia; Mehmood, Naunain; Dessì, Giorgia; Ariu, Federica; Carta, Carlo; Coghetto, Alberto; Pentcheva, Plamena; Gabrielli, Simona; Scala, Antonio; Varcasia, Antonio. - In: JOURNAL OF INFECTION IN DEVELOPING COUNTRIES. - ISSN 1972-2680. - 17:6(2023), pp. 762-781. [10.3855/jidc.9428]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1693742
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