Background and Objectives: Macular edema (ME) is a common complication of intermediate uveitis (IU). It is often responsible for a decrease in visual acuity (VA). Three distinct patterns of macular edema have been described in intermediate uveitis, namely, cystoid macular edema (CME), diffuse macular edema (DME), and serous retinal detachment (SRD). The current study aims to describe the characteristics of macular edema in young patients with idiopathic intermediate uveitis and to correlate its features with VA using spectral domain optical coherence tomography (SD-OCT). Materials and Methods: A total of 27 eyes from 18 patients with idiopathic IU complicated by ME were included in this retrospective study. All patients underwent SD-OCT; data were gathered at the onset of ME. Best-corrected VA (BCVA) was correlated with the morphological features of ME. Results: BCVA was negatively correlated with Ellipsoid Zone (EZ) disruption (p = 0.00021), cystoid pattern (p = 0.00021), central subfield thickness (CST) (p < 0.001), and serous retinal detachment (0.037). Conclusions: In ME secondary to idiopathic IU, VA negatively correlates with Ellipsoid Zone disruption and increases in CST. Moreover, vision is influenced by the presence of cysts in the inner nuclear and outer nuclear layers and by the neuroepithelium detachment.

Correlation between morphological characteristics of macular edema and visual acuity in young patients with idiopathic intermediate uveitis / Iannetti, Ludovico; Scarinci, Fabio; Alisi, Ludovico; Armentano, Marta; Sampalmieri, Lorenzo; La Cava, Maurizio; Gharbiya, Magda. - 59:3(2023). [10.3390/medicina59030529]

Correlation between morphological characteristics of macular edema and visual acuity in young patients with idiopathic intermediate uveitis

Iannetti, Ludovico
Primo
Conceptualization
;
Scarinci, Fabio
Secondo
Data Curation
;
Alisi, Ludovico
Writing – Original Draft Preparation
;
Armentano, Marta
Writing – Original Draft Preparation
;
Sampalmieri, Lorenzo
Writing – Review & Editing
;
La Cava, Maurizio
Penultimo
Conceptualization
;
Gharbiya, Magda
Ultimo
Supervision
2023

Abstract

Background and Objectives: Macular edema (ME) is a common complication of intermediate uveitis (IU). It is often responsible for a decrease in visual acuity (VA). Three distinct patterns of macular edema have been described in intermediate uveitis, namely, cystoid macular edema (CME), diffuse macular edema (DME), and serous retinal detachment (SRD). The current study aims to describe the characteristics of macular edema in young patients with idiopathic intermediate uveitis and to correlate its features with VA using spectral domain optical coherence tomography (SD-OCT). Materials and Methods: A total of 27 eyes from 18 patients with idiopathic IU complicated by ME were included in this retrospective study. All patients underwent SD-OCT; data were gathered at the onset of ME. Best-corrected VA (BCVA) was correlated with the morphological features of ME. Results: BCVA was negatively correlated with Ellipsoid Zone (EZ) disruption (p = 0.00021), cystoid pattern (p = 0.00021), central subfield thickness (CST) (p < 0.001), and serous retinal detachment (0.037). Conclusions: In ME secondary to idiopathic IU, VA negatively correlates with Ellipsoid Zone disruption and increases in CST. Moreover, vision is influenced by the presence of cysts in the inner nuclear and outer nuclear layers and by the neuroepithelium detachment.
2023
intermediate uveitis; macular edema; optical coherence tomography; retinal morphology; visual acuity
01 Pubblicazione su rivista::01a Articolo in rivista
Correlation between morphological characteristics of macular edema and visual acuity in young patients with idiopathic intermediate uveitis / Iannetti, Ludovico; Scarinci, Fabio; Alisi, Ludovico; Armentano, Marta; Sampalmieri, Lorenzo; La Cava, Maurizio; Gharbiya, Magda. - 59:3(2023). [10.3390/medicina59030529]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1692264
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