Background: Distal upper limb tremor during walking (TW) is frequently observed in Parkinson's disease (PD) but its clinical features are unknown. Objective: To characterize the occurrence and the clinical features of TW in comparison to the other types of tremors in PD. Methods: Fifty-one PD patients with rest tremor were evaluated off- and on-treatment. Occurrence, body distribution, severity and latency of TW and of other tremor types were assessed. Results: TW was present in 78% of the PD patients examined. TW body distribution and severity were similar to those of rest and re-emergent tremor but different from the postural tremor presented by the same patients. TW latency, observed in 85% of patients, was on average 5.8 s. Dopaminergic treatment significantly improved TW, rest, and re-emergent tremor severity but left TW latency unaffected. Conclusions: TW is a frequent motor sign in PD and is likely a clinical variant of rest tremor.
Distal Upper Limb Tremor during Walking in Parkinson's Disease / Costanzo, Matteo; Cutrona, Carolina; Leodori, Giorgio; De Bartolo, Maria Ilenia; Fabbrini, Andrea; Vivacqua, Giorgio; Conte, Antonella; Fabbrini, Giovanni; Berardelli, Alfredo; Belvisi, Daniele. - In: MOVEMENT DISORDERS CLINICAL PRACTICE. - ISSN 2330-1619. - 10:8(2023), pp. 1198-1202. [10.1002/mdc3.13814]
Distal Upper Limb Tremor during Walking in Parkinson's Disease
Costanzo, Matteo;Cutrona, Carolina;Leodori, Giorgio;De Bartolo, Maria Ilenia;Fabbrini, Andrea;Vivacqua, Giorgio;Conte, Antonella;Fabbrini, Giovanni;Berardelli, Alfredo;Belvisi, Daniele
2023
Abstract
Background: Distal upper limb tremor during walking (TW) is frequently observed in Parkinson's disease (PD) but its clinical features are unknown. Objective: To characterize the occurrence and the clinical features of TW in comparison to the other types of tremors in PD. Methods: Fifty-one PD patients with rest tremor were evaluated off- and on-treatment. Occurrence, body distribution, severity and latency of TW and of other tremor types were assessed. Results: TW was present in 78% of the PD patients examined. TW body distribution and severity were similar to those of rest and re-emergent tremor but different from the postural tremor presented by the same patients. TW latency, observed in 85% of patients, was on average 5.8 s. Dopaminergic treatment significantly improved TW, rest, and re-emergent tremor severity but left TW latency unaffected. Conclusions: TW is a frequent motor sign in PD and is likely a clinical variant of rest tremor.File | Dimensione | Formato | |
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Note: Costanzo_Distal Upper Limb Tremor_2023
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