Neurotrophins are closely related to stress, mental health and well-being. Initially synthesized as precursor proteins (proneurotrophins), they can influence both developing and mature neural circuits. For example, while pro Brain-Derived Neurotrophic Factor (proBDNF) and Nerve Growth Factor (NGF) are related to learning and neuronal plasticity, proNGF is related to nociception and neuro-degeneration. Levels of pro-neurotrophins are considerably changed in neurodegenerative pathologies such as Alzheimer’s and Parkinson’s diseases. In addition, stress was shown to suppress BDNF synthesis and exogenous administration of BDNF may produce an opposing response in some cases, emphasizing the importance of activating the body’s own resources. To this aim, we utilized the Quadrato Motor Training (QMT), a specifically-structured sensorimotor training, which was found to increase alpha synchronization and improve spatial cognition, reflectivity, creativity, as well as emotion regulation and general selfefficacy. Our studies demonstrated that proNGF and proBDNF vary following several weeks of QMT practice and are correlated with improved creativity, which is closely related to mental well-being. Together, these results support the idea that QMT is a useful integrated training that may aid in enhancing physical and mental well-being. In the current talk, we will discuss the implications of combining cognitively challenging physical training for healthy development and aging.

The molecular side of Quadrato Motor Training: implications for mental health / Venditti, Sabrina; Verdone, Loredana; Caserta, Micaela; Vetriani, Valerio; Dotan Ben-Soussan, Tal. - In: INTERNATIONAL JOURNAL OF MENTAL HEALTH & PSYCHIATRY. - ISSN 2471-4372. - 4:(2018), pp. 20-20. (Intervento presentato al convegno Global experts meeting on psychiatry and mental health tenutosi a Roma - Italia) [10.4172/2471-4372-C2-011].

The molecular side of Quadrato Motor Training: implications for mental health

Sabrina Venditti
Primo
Membro del Collaboration Group
;
Loredana Verdone
Secondo
Membro del Collaboration Group
;
Micaela Caserta
Membro del Collaboration Group
;
2018

Abstract

Neurotrophins are closely related to stress, mental health and well-being. Initially synthesized as precursor proteins (proneurotrophins), they can influence both developing and mature neural circuits. For example, while pro Brain-Derived Neurotrophic Factor (proBDNF) and Nerve Growth Factor (NGF) are related to learning and neuronal plasticity, proNGF is related to nociception and neuro-degeneration. Levels of pro-neurotrophins are considerably changed in neurodegenerative pathologies such as Alzheimer’s and Parkinson’s diseases. In addition, stress was shown to suppress BDNF synthesis and exogenous administration of BDNF may produce an opposing response in some cases, emphasizing the importance of activating the body’s own resources. To this aim, we utilized the Quadrato Motor Training (QMT), a specifically-structured sensorimotor training, which was found to increase alpha synchronization and improve spatial cognition, reflectivity, creativity, as well as emotion regulation and general selfefficacy. Our studies demonstrated that proNGF and proBDNF vary following several weeks of QMT practice and are correlated with improved creativity, which is closely related to mental well-being. Together, these results support the idea that QMT is a useful integrated training that may aid in enhancing physical and mental well-being. In the current talk, we will discuss the implications of combining cognitively challenging physical training for healthy development and aging.
2018
Global experts meeting on psychiatry and mental health
neurotrophins; neuronal plasticity; Quadrato Motor Training; well-being; mental health
04 Pubblicazione in atti di convegno::04c Atto di convegno in rivista
The molecular side of Quadrato Motor Training: implications for mental health / Venditti, Sabrina; Verdone, Loredana; Caserta, Micaela; Vetriani, Valerio; Dotan Ben-Soussan, Tal. - In: INTERNATIONAL JOURNAL OF MENTAL HEALTH & PSYCHIATRY. - ISSN 2471-4372. - 4:(2018), pp. 20-20. (Intervento presentato al convegno Global experts meeting on psychiatry and mental health tenutosi a Roma - Italia) [10.4172/2471-4372-C2-011].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1688707
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