Cardiac arrhythmias still represent a serious health issue, leading to adverse outcomes, such as heart failure and sudden death. Several drugs used to treat noncardiac diseases, including antibiotics or antipsychotics, can also be responsible for arrhythmia development. Therefore, a major challenge is a deeper comprehension of the molecular mechanisms regulating cardiac electro- physiology, together with the development of predic- tive tools aimed at understanding how a specific condition or drug can favor arrhythmic events.
New Insights into the role of GSK-3 in the regulation of human cardiac electrophysiology / Forte, Maurizio; Iacovone, Giuliano; Sciarretta, Sebastiano. - In: JACC. BASIC TO TRANSLATIONAL SCIENCE. - ISSN 2452-302X. - 7:10(2022), pp. 1018-1020. [10.1016/j.jacbts.2022.06.011]
New Insights into the role of GSK-3 in the regulation of human cardiac electrophysiology
Iacovone, Giuliano;Sciarretta, Sebastiano
2022
Abstract
Cardiac arrhythmias still represent a serious health issue, leading to adverse outcomes, such as heart failure and sudden death. Several drugs used to treat noncardiac diseases, including antibiotics or antipsychotics, can also be responsible for arrhythmia development. Therefore, a major challenge is a deeper comprehension of the molecular mechanisms regulating cardiac electro- physiology, together with the development of predic- tive tools aimed at understanding how a specific condition or drug can favor arrhythmic events.| File | Dimensione | Formato | |
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