The most common cause of end stage renal disease is diabetic nephropathy. An early diagnosis may allow an intervention to slow down disease progression. Recently, it has been hypothesized that glutathione-S-transferase (GST) activity may be a marker of severity of chronic kidney disease. In particular, a lower GST activity is present in healthy subjects compared to patients with nephropathy. In the present review we illustrate the scientific evidence underlying the possible role of GST activity in the development of diabetic nephropathy and we analyze its usefulness as a possible early biomarker of this diabetic complication

The possible role of glutathione-S-transferase activity in diabetic nephropathy / Tesauro, M; Nistico', S; Noce, A; Tarantino, A; Marrone, G; Costa, A; Rovella, V; Di Cola, G; Campia, U; Lauro, D; Cardillo, C; Di Daniele, N.. - In: INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY. - ISSN 0394-6320. - 28:1(2015), pp. 129-133. [10.1177/0394632015572564]

The possible role of glutathione-S-transferase activity in diabetic nephropathy

Nistico' S
;
2015

Abstract

The most common cause of end stage renal disease is diabetic nephropathy. An early diagnosis may allow an intervention to slow down disease progression. Recently, it has been hypothesized that glutathione-S-transferase (GST) activity may be a marker of severity of chronic kidney disease. In particular, a lower GST activity is present in healthy subjects compared to patients with nephropathy. In the present review we illustrate the scientific evidence underlying the possible role of GST activity in the development of diabetic nephropathy and we analyze its usefulness as a possible early biomarker of this diabetic complication
2015
biomarkers; diabetic nephropathy; glutathione-S-transferase; oxidative stress
01 Pubblicazione su rivista::01f Lettera, Nota
The possible role of glutathione-S-transferase activity in diabetic nephropathy / Tesauro, M; Nistico', S; Noce, A; Tarantino, A; Marrone, G; Costa, A; Rovella, V; Di Cola, G; Campia, U; Lauro, D; Cardillo, C; Di Daniele, N.. - In: INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY. - ISSN 0394-6320. - 28:1(2015), pp. 129-133. [10.1177/0394632015572564]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1687286
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