Heart failure (HF) represents a major health and economic issue, with increasing morbidity and mortality in spite of novel therapeutic weapons. The disappointing results of HF management may be due to the current thera-peutic approach based on the paradigm "one fits all", that cannot apply to a complex and multifaceted syndrome as HF. At this regard, the European Union is developing policies to move from reductionism to precision med-icine, in order to identify specific disease biomarkers and develop targeted therapeutic strategies. The institution of biobanks may represent the game changer in HF scenario, providing a collection of human biological materials with the related medical and epidemiological data fueling the development of personalized therapeutic approach and fostering current and/or future research projects.
Biobanks: the unmet need in heart failure management / Manzi, Giovanna; Mariani, Marco Valerio; Filomena, Domenico; Poscia, Roberto; Severino, Paolo; Iaconelli, Antonio; Recchioni, Tommaso; Madonna, Rosalinda; Vizza, Carmine Dario; Badagliacca, Roberto. - In: VASCULAR PHARMACOLOGY. - ISSN 1537-1891. - 150:(2023). [10.1016/j.vph.2023.107179]
Biobanks: the unmet need in heart failure management
Manzi, Giovanna;Mariani, Marco Valerio;Filomena, Domenico;Poscia, Roberto;Severino, Paolo;Recchioni, Tommaso;Vizza, Carmine Dario;Badagliacca, Roberto
2023
Abstract
Heart failure (HF) represents a major health and economic issue, with increasing morbidity and mortality in spite of novel therapeutic weapons. The disappointing results of HF management may be due to the current thera-peutic approach based on the paradigm "one fits all", that cannot apply to a complex and multifaceted syndrome as HF. At this regard, the European Union is developing policies to move from reductionism to precision med-icine, in order to identify specific disease biomarkers and develop targeted therapeutic strategies. The institution of biobanks may represent the game changer in HF scenario, providing a collection of human biological materials with the related medical and epidemiological data fueling the development of personalized therapeutic approach and fostering current and/or future research projects.File | Dimensione | Formato | |
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