Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. Methods: A three-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. Results: SCAD diagnosis was posed in 44 patients (30 males; median age: 64.5 yrs; prevalence of 1.99%, 95% CI, 1.45% to 2.66%). SCAD types D and B patients showed worse symptoms, higher FC values, needed more steroids and reached less likely complete remission. Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis / Tursi, Antonio; Piovani, Daniele; Brandimarte, Giovanni; Di Francesco, Mario; Elisei, Walter; Picchio, Marcello; Allegretta, Leonardo; Annunziata, Maria Laura; Bafutto, Mauro; Bassotti, Gabrio; Bianco, Maria Antonia; Colucci, Raffaele; Conigliaro, Rita; Dumitrascu, Dan L; Escalante, Ricardo; Ferrini, Luciano; Forti, Giacomo; Franceschi, Marilisa; Graziani, Maria Giovanna; Lammert, Frank; Latella, Giovanni; Maconi, Giovanni; Compare, Debora; Nardone, Gerardo; Camara De Castro Oliveira, Lucia; Oliveira, Enio Chaves; Papagrigoriadis, Savvas; Pietrzak, Anna; Pontone, Stefano; Stundiene, Ieva; Pranzo, Giuseppe; Reichert, Matthias Christian; Rodino, Stefano; Regula, Jaroslaw; Scaccianoce, Giuseppe; Scaldaferri, Franco; Vassallo, Roberto; Zampaletta, Costantino; Zullo, Angelo; Spaziani, Erasmo; Bonovas, Stefanos; Papa, Alfredo; Danese, Silvio. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 11:(2023), pp. 2088-2092. [10.14309/ajg.0000000000002362]
Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis
Di Mario, Francesco;Picchio, Marcello;Pontone, StefanoMembro del Collaboration Group
;Spaziani, Erasmo;
2023
Abstract
Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. Methods: A three-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. Results: SCAD diagnosis was posed in 44 patients (30 males; median age: 64.5 yrs; prevalence of 1.99%, 95% CI, 1.45% to 2.66%). SCAD types D and B patients showed worse symptoms, higher FC values, needed more steroids and reached less likely complete remission. Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
