Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. Methods: A three-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. Results: SCAD diagnosis was posed in 44 patients (30 males; median age: 64.5 yrs; prevalence of 1.99%, 95% CI, 1.45% to 2.66%). SCAD types D and B patients showed worse symptoms, higher FC values, needed more steroids and reached less likely complete remission. Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
Prevalence and natural history of segmental colitis associated with diverticulosis / Tursi, A., Piovani, D., Brandimarte, G., Di Francesco, M., Elisei, W., Picchio, M., Allegretta, L., Annunziata, M.L., Bafutto, M., Bassotti, G., Bianco, M.A., Colucci, R., Conigliaro, R., Dumitrascu, D.L., Escalante, R., Ferrini, L., Forti, G., Franceschi, M., Graziani, M.G., Lammert, F., et al.. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 118:11(2023), pp. 2088-2092. [10.14309/ajg.0000000000002362]
Prevalence and natural history of segmental colitis associated with diverticulosis
Di Mario, Francesco;Picchio, Marcello;Pontone, StefanoMembro del Collaboration Group
;Spaziani, Erasmo;
2023
Abstract
Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. Methods: A three-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. Results: SCAD diagnosis was posed in 44 patients (30 males; median age: 64.5 yrs; prevalence of 1.99%, 95% CI, 1.45% to 2.66%). SCAD types D and B patients showed worse symptoms, higher FC values, needed more steroids and reached less likely complete remission. Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.| File | Dimensione | Formato | |
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