Here we tested that standard eyes-closed resting-state electroencephalographic (rsEEG) rhythms may characterize patients with mild cognitive impairment due to chronic kidney disease at stages 3-4 (CKDMCI-3&4) in relation to CKDMCI patients under hemodialysis (CKDMCI-H) and MCI patients with cerebrovascular disease (CVMCI). Clinical and rsEEG data in 22 CKDMCI-3&4, 15 CKDMCI-H, 18 CVMCI, and 30 matched healthy control (HC) participants were available in a national archive. Spectral rsEEG power density was calculated from delta to gamma frequency bands at scalp electrodes. Results showed that (1) all MCI groups over the HC group showed decreased occipital rsEEG alpha power density; (2) compared to the HC and CVMCI groups, the two CKDMCI groups had higher rsEEG delta-theta power density; and (3) the CKDMCI-3&4 group showed the lowest parietal rsEEG alpha power density. The present rsEEG measures may be useful to monitor the impact of circulating uremic toxins on brain regulation of cortical arousal for quiet vigilance in CKDMCI patients.

Resting state EEG rhythms in different stages of chronic kidney disease with mild cognitive impairment / Lizio, Roberta; Lopez, Susanna; Babiloni, Claudio; Del Percio, Claudio; Noce, Giuseppe; Losurdo, Antonia; Vernò, Lucia; De Tommaso, Marina; Montemurno, Anna; Dalfino, Giuseppe; Cirillo, Pietro; Soricelli, Andrea; Ferri, Raffaele; Catania, Valentina; Nobili, Flavio; Giubilei, Franco; Buttinelli, Carla; Frisoni, Giovanni B.; Stocchi, Fabrizio; Scisci, Anna Maria; Mastrofilippo, Nicola; Procaccini, Deni Aldo; Gesualdo, Loreto. - In: NEUROBIOLOGY OF AGING. - ISSN 0197-4580. - (2023), pp. 70-79. [10.1016/j.neurobiolaging.2023.05.014]

Resting state EEG rhythms in different stages of chronic kidney disease with mild cognitive impairment

Lizio, Roberta;Lopez, Susanna;Babiloni, Claudio;Del Percio, Claudio;Noce, Giuseppe;De Tommaso, Marina;Cirillo, Pietro;Giubilei, Franco;Buttinelli, Carla;Stocchi, Fabrizio;
2023

Abstract

Here we tested that standard eyes-closed resting-state electroencephalographic (rsEEG) rhythms may characterize patients with mild cognitive impairment due to chronic kidney disease at stages 3-4 (CKDMCI-3&4) in relation to CKDMCI patients under hemodialysis (CKDMCI-H) and MCI patients with cerebrovascular disease (CVMCI). Clinical and rsEEG data in 22 CKDMCI-3&4, 15 CKDMCI-H, 18 CVMCI, and 30 matched healthy control (HC) participants were available in a national archive. Spectral rsEEG power density was calculated from delta to gamma frequency bands at scalp electrodes. Results showed that (1) all MCI groups over the HC group showed decreased occipital rsEEG alpha power density; (2) compared to the HC and CVMCI groups, the two CKDMCI groups had higher rsEEG delta-theta power density; and (3) the CKDMCI-3&4 group showed the lowest parietal rsEEG alpha power density. The present rsEEG measures may be useful to monitor the impact of circulating uremic toxins on brain regulation of cortical arousal for quiet vigilance in CKDMCI patients.
2023
resting state electroencephalographic (rsEEG) rhythms; mild cognitive impairment (MCI); chronic kidney disease (CKD); hemodialysis; cerebrovascular disease
01 Pubblicazione su rivista::01a Articolo in rivista
Resting state EEG rhythms in different stages of chronic kidney disease with mild cognitive impairment / Lizio, Roberta; Lopez, Susanna; Babiloni, Claudio; Del Percio, Claudio; Noce, Giuseppe; Losurdo, Antonia; Vernò, Lucia; De Tommaso, Marina; Montemurno, Anna; Dalfino, Giuseppe; Cirillo, Pietro; Soricelli, Andrea; Ferri, Raffaele; Catania, Valentina; Nobili, Flavio; Giubilei, Franco; Buttinelli, Carla; Frisoni, Giovanni B.; Stocchi, Fabrizio; Scisci, Anna Maria; Mastrofilippo, Nicola; Procaccini, Deni Aldo; Gesualdo, Loreto. - In: NEUROBIOLOGY OF AGING. - ISSN 0197-4580. - (2023), pp. 70-79. [10.1016/j.neurobiolaging.2023.05.014]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1682372
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