Quality of life (QoL) is an important and modifiable concept that should be taken into considerations during treatment allocation in cancer patients. In the last 15 years, studies have reported that supplementation with oocyte extract, which is pivotal during the stage of cell differentiation, may be associated with reduction or suppression of tumour growth and may be, in fact, beneficial in patients with liver tumours. Here, we designed a multicentre, double-blind, randomized clinical trial to assess whether the QoL of patients operated for liver tumours was impacted by receiving a supplement of oocyte extract postoperatively. As shown, the supplement of oocyte extract modifies the QoL after liver surgery by enhancing the functional recovery for many of the QoL items considered. The same result was not recorded with the placebo
Impact of Oocyte Extract Supplement on Quality of Life after Hepatectomy for Liver Tumours: A Prospective, Multicentre, Double-Blind Randomized Clinical Trial / Donadon, Matteo; Palmisano, Angela; Bizzarri, Mariano; Ceriani, Roberto; Veneroni, Luigi; Donati, Gabriele; Tassinari, Davide; Viola, Massimo Giuseppe; Tamburini, Emiliano; Torzilli, Guido. - In: CANCERS. - ISSN 2072-6694. - 15:10(2023), p. 2809. [10.3390/cancers15102809]
Impact of Oocyte Extract Supplement on Quality of Life after Hepatectomy for Liver Tumours: A Prospective, Multicentre, Double-Blind Randomized Clinical Trial
Bizzarri, Mariano;
2023
Abstract
Quality of life (QoL) is an important and modifiable concept that should be taken into considerations during treatment allocation in cancer patients. In the last 15 years, studies have reported that supplementation with oocyte extract, which is pivotal during the stage of cell differentiation, may be associated with reduction or suppression of tumour growth and may be, in fact, beneficial in patients with liver tumours. Here, we designed a multicentre, double-blind, randomized clinical trial to assess whether the QoL of patients operated for liver tumours was impacted by receiving a supplement of oocyte extract postoperatively. As shown, the supplement of oocyte extract modifies the QoL after liver surgery by enhancing the functional recovery for many of the QoL items considered. The same result was not recorded with the placeboI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
