The inadequate dietary intake of Vitamin D and Vitamin K is an easily reversible factor favoring IBD-associated bone loss, but data on Vitamin K are lacking. A 28-item quantitative food frequency questionnaire was administered to 193 IBD patients (89 Crohn’s disease and 104 ulcerative colitis), and 199 controls. Patients’ demographics, clinical and laboratory findings were analyzed in relation to recommended daily allowances. VitD intake was inadequate both in the IBD and control patients (8.3 ± 4.5 µg/day in IBD, 53.1% RDA, and 9.7 ± 5.9 µg/day, 63.2% RDA, respectively). Conversely, the mean ViK intake was less than adequate in IBD, at 116.7 ± 116.3 µg/day (78.7% RDA), and high in controls, at 203.1 ± 166.9 µg/day (138.8% RDA). Nonetheless, due to marked interindividual differences, diets were severely lacking VitK in 40% of UC and 49% of CD patients, more so in females and those with active disease. The intake of Vit D was non-significantly lower in colitis than that in Crohn’s disease (7.9 vs. 8.7 µg/day). The opposite was observed for VitK (123.5 vs. 107.0 µg/day). Thus, the diet lacks the micronutrients involved in bone wellbeing in a large proportion of IBD patients. While VitD supplementation is the rule, VitK shortages need proactive nutritional intervention. Keywords: IBD; vitamin K; vitamin D; diet in IBD

Low Vitamin K and Vitamin D Dietary Intake in Patients with Inflammatory Bowel Diseases / Vernia, F.; Burrelli Scotti, G.; Bertetti, N. S.; Donato, G.; Necozione, S.; Vernia, P.; Pallotta, N.. - In: NUTRIENTS. - ISSN 2072-6643. - 15:7(2023). [10.3390/nu15071678]

Low Vitamin K and Vitamin D Dietary Intake in Patients with Inflammatory Bowel Diseases

Burrelli Scotti G.
Secondo
Investigation
;
Bertetti N. S.;Donato G.;Vernia P.
Penultimo
Writing – Review & Editing
;
Pallotta N.
Ultimo
Supervision
2023

Abstract

The inadequate dietary intake of Vitamin D and Vitamin K is an easily reversible factor favoring IBD-associated bone loss, but data on Vitamin K are lacking. A 28-item quantitative food frequency questionnaire was administered to 193 IBD patients (89 Crohn’s disease and 104 ulcerative colitis), and 199 controls. Patients’ demographics, clinical and laboratory findings were analyzed in relation to recommended daily allowances. VitD intake was inadequate both in the IBD and control patients (8.3 ± 4.5 µg/day in IBD, 53.1% RDA, and 9.7 ± 5.9 µg/day, 63.2% RDA, respectively). Conversely, the mean ViK intake was less than adequate in IBD, at 116.7 ± 116.3 µg/day (78.7% RDA), and high in controls, at 203.1 ± 166.9 µg/day (138.8% RDA). Nonetheless, due to marked interindividual differences, diets were severely lacking VitK in 40% of UC and 49% of CD patients, more so in females and those with active disease. The intake of Vit D was non-significantly lower in colitis than that in Crohn’s disease (7.9 vs. 8.7 µg/day). The opposite was observed for VitK (123.5 vs. 107.0 µg/day). Thus, the diet lacks the micronutrients involved in bone wellbeing in a large proportion of IBD patients. While VitD supplementation is the rule, VitK shortages need proactive nutritional intervention. Keywords: IBD; vitamin K; vitamin D; diet in IBD
2023
IBD; diet in IBD; vitamin D; vitamin K
01 Pubblicazione su rivista::01a Articolo in rivista
Low Vitamin K and Vitamin D Dietary Intake in Patients with Inflammatory Bowel Diseases / Vernia, F.; Burrelli Scotti, G.; Bertetti, N. S.; Donato, G.; Necozione, S.; Vernia, P.; Pallotta, N.. - In: NUTRIENTS. - ISSN 2072-6643. - 15:7(2023). [10.3390/nu15071678]
File allegati a questo prodotto
File Dimensione Formato  
Vernia_Low-Vitamin_2023.pdf

accesso aperto

Note: original article
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 289.75 kB
Formato Adobe PDF
289.75 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1681659
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact