Autophagy controls cell homeostasis and provides a rapid response to a variety of stresses. Although many steps of the autophagy process have been elucidated, how they are temporally regulated is less well characterized. Recently, we reported that dynamic interaction of the pro-autophagic factor AMBRA1 with CULLIN E3 ubiquitin ligases ensures the timely onset and termination of the autophagy response.
Temporal regulation of autophagy response by the CULLIN 4-AMBRA1-CULLIN 5 axis / Antonioli, M.; Albiero, F.; Piacentini, M.; Fimia, G. M.. - In: MOLECULAR & CELLULAR ONCOLOGY. - ISSN 2372-3556. - 3:5(2016). [10.1080/23723556.2015.1008304]
Temporal regulation of autophagy response by the CULLIN 4-AMBRA1-CULLIN 5 axis
Fimia G. M.Conceptualization
2016
Abstract
Autophagy controls cell homeostasis and provides a rapid response to a variety of stresses. Although many steps of the autophagy process have been elucidated, how they are temporally regulated is less well characterized. Recently, we reported that dynamic interaction of the pro-autophagic factor AMBRA1 with CULLIN E3 ubiquitin ligases ensures the timely onset and termination of the autophagy response.File allegati a questo prodotto
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
