Introduction: The present study aimed at evaluating Italian epidemiological trends of pediatric inflammatory bowel diseases (IBD) over the period 2009-2018.Materials and methods: Data from 1969 patients enrolled in the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition Registry, by 49 pediatric IBD centers throughout the country, were analyzed, comparing three different time intervals (2009-2012, 2013-2015, 2016-2018).Results: The number of new IBD diagnoses ranged from 175 to 219 per year, evenly distributed over the examined period of time. From 2009 to 2018, the minimal incidence ranged from 1.59 to 2.04 /10 5 inhabitants aged < 18 years, with an overall slight predominance of ulcerative colitis (UC) over Crohn's disease (CD) (ratio: 1.1). Mean diagnostic delay was 6.8 months for CD and 4.1 months for UC, with a significant reduction for CD when comparing the three-time intervals ( p = 0.008). The most frequent disease locations according to the Paris classification were ileocolonic for CD (41.3%) and pancolitis for UC (54.6%).Conclusions: The minimal incidence rate in Italy seems to have stabilized over the last two decades, even if it has increased when compared to previous reports. UC is still slightly more prevalent than CD in our country. Diagnostic delay significantly decreased for CD, reflecting an improved diagnostic capacity. (c) 2022 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Epidemiological trends of pediatric IBD in Italy: A 10-year analysis of the Italian society of pediatric gastroenterology, hepatology and nutrition registry / Alvisi, Patrizia; Labriola, Flavio; Scarallo, Luca; Gandullia, Paolo; Knafelz, Daniela; Bramuzzo, Matteo; Zuin, Giovanna; Pastore, Maria Rosa; Illiceto, Maria Teresa; Miele, Erasmo; Graziano, Francesco; Romano, Claudio; Bartoletti, Daniela; Oliva, Salvatore; Arrigo, Serena; Bracci, Fiammetta; Renzo, Sara; Agrusti, Anna; Aloi, Marina; Lionetti, Paolo. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 54:4(2022), pp. 469-476. [10.1016/j.dld.2021.12.018]

Epidemiological trends of pediatric IBD in Italy: A 10-year analysis of the Italian society of pediatric gastroenterology, hepatology and nutrition registry

Oliva, Salvatore;Aloi, Marina;
2022

Abstract

Introduction: The present study aimed at evaluating Italian epidemiological trends of pediatric inflammatory bowel diseases (IBD) over the period 2009-2018.Materials and methods: Data from 1969 patients enrolled in the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition Registry, by 49 pediatric IBD centers throughout the country, were analyzed, comparing three different time intervals (2009-2012, 2013-2015, 2016-2018).Results: The number of new IBD diagnoses ranged from 175 to 219 per year, evenly distributed over the examined period of time. From 2009 to 2018, the minimal incidence ranged from 1.59 to 2.04 /10 5 inhabitants aged < 18 years, with an overall slight predominance of ulcerative colitis (UC) over Crohn's disease (CD) (ratio: 1.1). Mean diagnostic delay was 6.8 months for CD and 4.1 months for UC, with a significant reduction for CD when comparing the three-time intervals ( p = 0.008). The most frequent disease locations according to the Paris classification were ileocolonic for CD (41.3%) and pancolitis for UC (54.6%).Conclusions: The minimal incidence rate in Italy seems to have stabilized over the last two decades, even if it has increased when compared to previous reports. UC is still slightly more prevalent than CD in our country. Diagnostic delay significantly decreased for CD, reflecting an improved diagnostic capacity. (c) 2022 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
2022
Epidemiological trends; Italy; Pediatric IBD
01 Pubblicazione su rivista::01a Articolo in rivista
Epidemiological trends of pediatric IBD in Italy: A 10-year analysis of the Italian society of pediatric gastroenterology, hepatology and nutrition registry / Alvisi, Patrizia; Labriola, Flavio; Scarallo, Luca; Gandullia, Paolo; Knafelz, Daniela; Bramuzzo, Matteo; Zuin, Giovanna; Pastore, Maria Rosa; Illiceto, Maria Teresa; Miele, Erasmo; Graziano, Francesco; Romano, Claudio; Bartoletti, Daniela; Oliva, Salvatore; Arrigo, Serena; Bracci, Fiammetta; Renzo, Sara; Agrusti, Anna; Aloi, Marina; Lionetti, Paolo. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 54:4(2022), pp. 469-476. [10.1016/j.dld.2021.12.018]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1679785
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 9
social impact