A clinical strain of Klebsiella pneumoniae typed as sequence type 307 carrying three different alleles of the flu gene encoding the Escherichia coli virulence factor antigen 43 associated with biofilm formation was detected and characterized. The flu alleles are located in the chromosome inside putative integrative conjugative elements. The strain displays the phenotypes associated with Ag43, i.e. bi-phasic colony morphology and enhanced biofilm production. Furthermore, the strain produces low amount of capsule known to affect Ag43 function. Analysis of 1431 worldwide deposited genomes revealed that 3.7% Klebsiella pneumoniae carry one or two flu alleles.

Klebsiella pneumoniae carrying multiple alleles of antigen 43-encoding gene of Escherichia coli associated with biofilm formation / Tambassi, Martina; Passarini, Elena; Menozzi, Ilaria; Berni, Melissa; Bracchi, Chiara; Dodi, Alessandra; Bolzoni, Luca; Scaltriti, Erika; Morganti, Marina; Ferrarini, Giulia; Sordi, Laura; Sarti, Mario; Ambretti &, Simone; Pongolini, Stefano. - In: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. - ISSN 0934-9723. - 42:3(2023), pp. 371-377. [10.1007/s10096-023-04552-6]

Klebsiella pneumoniae carrying multiple alleles of antigen 43-encoding gene of Escherichia coli associated with biofilm formation

Elena Passarini;
2023

Abstract

A clinical strain of Klebsiella pneumoniae typed as sequence type 307 carrying three different alleles of the flu gene encoding the Escherichia coli virulence factor antigen 43 associated with biofilm formation was detected and characterized. The flu alleles are located in the chromosome inside putative integrative conjugative elements. The strain displays the phenotypes associated with Ag43, i.e. bi-phasic colony morphology and enhanced biofilm production. Furthermore, the strain produces low amount of capsule known to affect Ag43 function. Analysis of 1431 worldwide deposited genomes revealed that 3.7% Klebsiella pneumoniae carry one or two flu alleles.
2023
Klebsiella pneumoniae; Antigen 43; Biofilm; ST307; Colistin resistance; Mcr; Capsule;
01 Pubblicazione su rivista::01a Articolo in rivista
Klebsiella pneumoniae carrying multiple alleles of antigen 43-encoding gene of Escherichia coli associated with biofilm formation / Tambassi, Martina; Passarini, Elena; Menozzi, Ilaria; Berni, Melissa; Bracchi, Chiara; Dodi, Alessandra; Bolzoni, Luca; Scaltriti, Erika; Morganti, Marina; Ferrarini, Giulia; Sordi, Laura; Sarti, Mario; Ambretti &, Simone; Pongolini, Stefano. - In: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. - ISSN 0934-9723. - 42:3(2023), pp. 371-377. [10.1007/s10096-023-04552-6]
File allegati a questo prodotto
File Dimensione Formato  
Tambassi_Klebsiella_2023.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 1.81 MB
Formato Adobe PDF
1.81 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1679298
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact