Oligometastatic disease has been described as an intermediate clinical state between localized cancer and systemically metastasized disease. Recent clinical studies have shown prolonged survival when aggressive locoregional approaches are added to systemic therapies in patients with oligometastases. The aim of this review is to outline the newest options to treat oligometastatic colorectal cancer (CRC), also considering its molecular patterns. We present an overview of the available local treatment strategies, including surgical procedures, stereotactic body radiation therapy (SBRT), thermal ablation, as well as trans-arterial chemoembolization (TACE) and selective internal radiotherapy (SIRT). Moreover, since imaging methods provide crucial information for the early diagnosis and management of oligometastatic CRC, we discuss the role of modern radiologic techniques in selecting patients that are amenable to potentially curative locoregional treatments.

The management of oligometastatic disease in colorectal cancer: present strategies and future perspectives / Carconi, Catia; Cerreti, Micaela; Roberto, Michela; Arrivi, Giulia; D'Ambrosio, Giancarlo; De Felice, Francesca; Di Civita, Mattia Alberto; Iafrate, Franco; Lucatelli, Pierleone; Magliocca, Fabio Massimo; Picchetto, Andrea; Picone, Vincenzo; Catalano, Carlo; Cortesi, Enrico; Tombolini, Vincenzo; Mazzuca, Federica; Tomao, Silverio. - In: CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY. - ISSN 1879-0461. - 186:(2023). [10.1016/j.critrevonc.2023.103990]

The management of oligometastatic disease in colorectal cancer: present strategies and future perspectives

Cerreti, Micaela
Secondo
;
Roberto, Michela
;
Arrivi, Giulia;D'Ambrosio, Giancarlo;De Felice, Francesca;Di Civita, Mattia Alberto;Iafrate, Franco;Lucatelli, Pierleone;Magliocca, Fabio Massimo;Picchetto, Andrea;Picone, Vincenzo;Catalano, Carlo;Cortesi, Enrico;Tombolini, Vincenzo;Mazzuca, Federica
Penultimo
;
Tomao, Silverio
Ultimo
2023

Abstract

Oligometastatic disease has been described as an intermediate clinical state between localized cancer and systemically metastasized disease. Recent clinical studies have shown prolonged survival when aggressive locoregional approaches are added to systemic therapies in patients with oligometastases. The aim of this review is to outline the newest options to treat oligometastatic colorectal cancer (CRC), also considering its molecular patterns. We present an overview of the available local treatment strategies, including surgical procedures, stereotactic body radiation therapy (SBRT), thermal ablation, as well as trans-arterial chemoembolization (TACE) and selective internal radiotherapy (SIRT). Moreover, since imaging methods provide crucial information for the early diagnosis and management of oligometastatic CRC, we discuss the role of modern radiologic techniques in selecting patients that are amenable to potentially curative locoregional treatments.
2023
colorectal cancer (CRC); oligometastatic disease (OMD); radiofrequency ablation (RFA); selective internal radiotherapy (SIRT); stereotactic body radiation therapy (SBRT); trans-arterial chemoembolization (TACE)
01 Pubblicazione su rivista::01a Articolo in rivista
The management of oligometastatic disease in colorectal cancer: present strategies and future perspectives / Carconi, Catia; Cerreti, Micaela; Roberto, Michela; Arrivi, Giulia; D'Ambrosio, Giancarlo; De Felice, Francesca; Di Civita, Mattia Alberto; Iafrate, Franco; Lucatelli, Pierleone; Magliocca, Fabio Massimo; Picchetto, Andrea; Picone, Vincenzo; Catalano, Carlo; Cortesi, Enrico; Tombolini, Vincenzo; Mazzuca, Federica; Tomao, Silverio. - In: CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY. - ISSN 1879-0461. - 186:(2023). [10.1016/j.critrevonc.2023.103990]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1678632
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