Background: Urolithiasis is a chronic condition, and it has been associated with a significant negative impact on patients' health-related quality of life (HRQOL). Several tools to assess patients' HRQOL have been validated in Italian, however disease-specific HRQOL instruments are still lacking. We aimed to develop and validate the Italian version of the WISQOL (I-WISQOL) in patients with urolithiasis. Methods: The Italian version of the WISQOL was developed in a multistep process involving primary translation, back-translation, and pilot testing among a group of patients (N.=10). Patients presenting with urolithiasis were prospectively recruited from the outpatient stone clinics and completed both questionnaire WISQOL and SF-36. Demographic information, as well as medical and surgical data, were obtained through an interview. Internal consistency of the I-WISQOL was obtained with Cronbach's α. Correlation of total scores of the I-WISQOL and SF36 was assessed to determine convergent validity using Spearman Rho. Correlations between clinical variables and results from the I-WISQOL were analyzed to descriptively assess the association of interest. Results: A total of 93 participants were evaluated and completed the Italian version of the I-WISQOL. The I-WISQOL demonstrated excellent internal consistency (Cronbach's α 0.95) and good convergent validity with the validated SF-36 (Spearman Rho r=0.70, P<0.001). Using ANOVA analysis, a significant decline in WISQOL Score was noted with the increasing number of renal colics (P=0.0543), ER visits (P=0.037), number of inpatient hospitalization (P=0.025). At multivariate analysis, worse WISQOL total score was predicted by a greater number of renal colic events (ß=-4.92 [-8.81-1.04], P=0.014) and by a greater number inpatient hospitalization (ß=-7.31 [-14.35 -0.26], P=0.042). Conclusions: The I-WISQOL is an internally consistent and valid instrument to assess HRQOL in Italian-speaking patients with kidney stones. Its use in clinical practice should be implemented in order to tailor the management of each patient.

Translation and validation of the Italian version of the Wisconsin Stone Quality of Life Questionnaire (I-WISQOL) for assessing quality of life in patients with urolithiasis / Salciccia, Stefano; Maggi, Martina; Frisenda, Marco; Finistauri Guacci, Lucia; Hoxha, Sanie; Licari, Leslie C; Viscuso, Pietro; Gentilucci, Alessandro; Del Giudice, Francesco; DE Berardinis, Ettore; Cattarino, Susanna; Mariotti, Gianna; Tufano, Antonio; DE Dominicis, Mauro; Ricciuti, Gian P; Sciarra, Alessandro; Penniston, Kristina L; Moriconi, Martina. - In: MINERVA UROLOGY AND NEPHROLOGY. - ISSN 2724-6442. - (2023). [10.23736/S2724-6051.23.04882-6]

Translation and validation of the Italian version of the Wisconsin Stone Quality of Life Questionnaire (I-WISQOL) for assessing quality of life in patients with urolithiasis

Salciccia, Stefano;Frisenda, Marco;Finistauri Guacci, Lucia;Licari, Leslie C;Viscuso, Pietro;Gentilucci, Alessandro;DE Berardinis, Ettore;Cattarino, Susanna;Tufano, Antonio;Ricciuti, Gian P;Sciarra, Alessandro;Moriconi, Martina
2023

Abstract

Background: Urolithiasis is a chronic condition, and it has been associated with a significant negative impact on patients' health-related quality of life (HRQOL). Several tools to assess patients' HRQOL have been validated in Italian, however disease-specific HRQOL instruments are still lacking. We aimed to develop and validate the Italian version of the WISQOL (I-WISQOL) in patients with urolithiasis. Methods: The Italian version of the WISQOL was developed in a multistep process involving primary translation, back-translation, and pilot testing among a group of patients (N.=10). Patients presenting with urolithiasis were prospectively recruited from the outpatient stone clinics and completed both questionnaire WISQOL and SF-36. Demographic information, as well as medical and surgical data, were obtained through an interview. Internal consistency of the I-WISQOL was obtained with Cronbach's α. Correlation of total scores of the I-WISQOL and SF36 was assessed to determine convergent validity using Spearman Rho. Correlations between clinical variables and results from the I-WISQOL were analyzed to descriptively assess the association of interest. Results: A total of 93 participants were evaluated and completed the Italian version of the I-WISQOL. The I-WISQOL demonstrated excellent internal consistency (Cronbach's α 0.95) and good convergent validity with the validated SF-36 (Spearman Rho r=0.70, P<0.001). Using ANOVA analysis, a significant decline in WISQOL Score was noted with the increasing number of renal colics (P=0.0543), ER visits (P=0.037), number of inpatient hospitalization (P=0.025). At multivariate analysis, worse WISQOL total score was predicted by a greater number of renal colic events (ß=-4.92 [-8.81-1.04], P=0.014) and by a greater number inpatient hospitalization (ß=-7.31 [-14.35 -0.26], P=0.042). Conclusions: The I-WISQOL is an internally consistent and valid instrument to assess HRQOL in Italian-speaking patients with kidney stones. Its use in clinical practice should be implemented in order to tailor the management of each patient.
2023
stone, urinary tract
01 Pubblicazione su rivista::01a Articolo in rivista
Translation and validation of the Italian version of the Wisconsin Stone Quality of Life Questionnaire (I-WISQOL) for assessing quality of life in patients with urolithiasis / Salciccia, Stefano; Maggi, Martina; Frisenda, Marco; Finistauri Guacci, Lucia; Hoxha, Sanie; Licari, Leslie C; Viscuso, Pietro; Gentilucci, Alessandro; Del Giudice, Francesco; DE Berardinis, Ettore; Cattarino, Susanna; Mariotti, Gianna; Tufano, Antonio; DE Dominicis, Mauro; Ricciuti, Gian P; Sciarra, Alessandro; Penniston, Kristina L; Moriconi, Martina. - In: MINERVA UROLOGY AND NEPHROLOGY. - ISSN 2724-6442. - (2023). [10.23736/S2724-6051.23.04882-6]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1678103
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