We propose a photonic biochip which combines optical and microfluidic channels to exploit the potential of gold nanorods (GNRs) in developing light-assisted antimicrobial therapies. The proposed chip is obtained by coupling two separately processed PolyDiMethylSiloxane (PDMS) substrates in which microfluidic channels, conveying biological fluid flow, and optical waveguides, confining near-infrared light, interact. The light activates the localized plasmonic resonance of GNRs dispersed in a film deposited on the functionalized PDMS substrates. This paper uses experimental measurements and numerical simulations based on Finite Element Method software tools to optimize the final design in terms of suitable GNRs irradiation, dimensions, aspect ratio, density, and distribution.

All-optical biophotonic and microfluidic circuits for photo-thermal applications / Santini, C.; De Sio, L.; Petronella, F.; D'Alessandro, A.. - 1005 LNEE:(2023), pp. 178-183. (Intervento presentato al convegno 53rd Annual Meeting of the Italian Electronics Society, SIE 2022 tenutosi a Pizzo) [10.1007/978-3-031-26066-7_28].

All-optical biophotonic and microfluidic circuits for photo-thermal applications

Santini C.
Primo
;
De Sio L.
Secondo
;
d'Alessandro A.
Ultimo
2023

Abstract

We propose a photonic biochip which combines optical and microfluidic channels to exploit the potential of gold nanorods (GNRs) in developing light-assisted antimicrobial therapies. The proposed chip is obtained by coupling two separately processed PolyDiMethylSiloxane (PDMS) substrates in which microfluidic channels, conveying biological fluid flow, and optical waveguides, confining near-infrared light, interact. The light activates the localized plasmonic resonance of GNRs dispersed in a film deposited on the functionalized PDMS substrates. This paper uses experimental measurements and numerical simulations based on Finite Element Method software tools to optimize the final design in terms of suitable GNRs irradiation, dimensions, aspect ratio, density, and distribution.
2023
53rd Annual Meeting of the Italian Electronics Society, SIE 2022
Nanophotonics, Microfluidics, Nanoplasmonics, Integrated optics, Nanoparticles
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
All-optical biophotonic and microfluidic circuits for photo-thermal applications / Santini, C.; De Sio, L.; Petronella, F.; D'Alessandro, A.. - 1005 LNEE:(2023), pp. 178-183. (Intervento presentato al convegno 53rd Annual Meeting of the Italian Electronics Society, SIE 2022 tenutosi a Pizzo) [10.1007/978-3-031-26066-7_28].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1677795
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