(1) Background: The aim of this review was to determine the state of clinical practice in the role of the combined approach of embolization and ablation in patients with secondary liver lesions greater than 3 cm who are not candidates for surgery, and to study its safety and efficacy. (2) Methods: Two reviewers conducted the literature search independently. Eight articles on the combined approach of embolization and ablation in secondary liver lesions were selected. (3) Results: The studies were published between 2009 and 2020. Two studies were prospective in design. The sample size was < 100 patients for all studies. All studies demonstrated the safety of the combined approach based on the low complication rate. Some studies lamented non-uniform systemic chemotherapy regimens and the variability in the sequence of embolization and ablation. (4) Conclusions: This review presents the combined approach of ablation and embolization in liver lesions greater than 3 cm as a safe therapeutic procedure with positive effects on patient survival. Prospective and multicentric studies are needed to further evaluate its efficacy.

Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature / Faiella, Eliodoro; Calabrese, Alessandro; Santucci, Domiziana; de Felice, Carlo; Pusceddu, Claudio; Fior, Davide; Fontana, Federico; Piacentino, Filippo; Moramarco, Lorenzo Paolo; Muraca, Rosa Maria; Venturini, Massimo. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 11:19(2022), p. 5576. [10.3390/jcm11195576]

Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature

Calabrese, Alessandro;de Felice, Carlo;
2022

Abstract

(1) Background: The aim of this review was to determine the state of clinical practice in the role of the combined approach of embolization and ablation in patients with secondary liver lesions greater than 3 cm who are not candidates for surgery, and to study its safety and efficacy. (2) Methods: Two reviewers conducted the literature search independently. Eight articles on the combined approach of embolization and ablation in secondary liver lesions were selected. (3) Results: The studies were published between 2009 and 2020. Two studies were prospective in design. The sample size was < 100 patients for all studies. All studies demonstrated the safety of the combined approach based on the low complication rate. Some studies lamented non-uniform systemic chemotherapy regimens and the variability in the sequence of embolization and ablation. (4) Conclusions: This review presents the combined approach of ablation and embolization in liver lesions greater than 3 cm as a safe therapeutic procedure with positive effects on patient survival. Prospective and multicentric studies are needed to further evaluate its efficacy.
2022
embolization; interventional radiology; secondary liver lesions
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature / Faiella, Eliodoro; Calabrese, Alessandro; Santucci, Domiziana; de Felice, Carlo; Pusceddu, Claudio; Fior, Davide; Fontana, Federico; Piacentino, Filippo; Moramarco, Lorenzo Paolo; Muraca, Rosa Maria; Venturini, Massimo. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 11:19(2022), p. 5576. [10.3390/jcm11195576]
File allegati a questo prodotto
File Dimensione Formato  
faiella 2022.pdf

accesso aperto

Note: Faiella_Combined Trans-Arterial Embolization_2022
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 371.58 kB
Formato Adobe PDF
371.58 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1677763
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact