Coagulation and inflammation are tightly and reciprocally regulated. Inflammation initiates clotting, decreases the activity of natural anticoagulant mechanisms and impairs the fibrinolytic system. Thrombin is the main effector protease in hemostasis and it also plays a role in various non-hemostatic biological and pathophysiologic processes, predominantly mediated through activation of protease-activated receptors (PARs).
Thrombin in the peripheral nervous system as regulator of Schwann cell neurotrophic potentials / Fabrizi, C.; Pompili, E.; Ciraci, V.; Leone, S.; Matassa, R.; Familiari, G.; Fumagalli, L.. - In: ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY. - ISSN 1122-6714. - 123:1(2018). [10.13128/ijae-11386]
Thrombin in the peripheral nervous system as regulator of Schwann cell neurotrophic potentials
Fabrizi C.Primo
;Pompili E.
Secondo
;Ciraci V.;Leone S.;Matassa R.;Familiari G.Penultimo
;Fumagalli L.Ultimo
2018
Abstract
Coagulation and inflammation are tightly and reciprocally regulated. Inflammation initiates clotting, decreases the activity of natural anticoagulant mechanisms and impairs the fibrinolytic system. Thrombin is the main effector protease in hemostasis and it also plays a role in various non-hemostatic biological and pathophysiologic processes, predominantly mediated through activation of protease-activated receptors (PARs).| File | Dimensione | Formato | |
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