Background: Subarachnoid hemorrhage (SAH) due to a middle cerebral artery (MCA) aneurysm rupture is often associated with an intracerebral hematoma (ICH) or intrasylvian hematoma (ISH). Methods: We reviewed 163 patients with ruptured MCA aneurysms associated with pure SAH or SAH plus ICH or ISH. The patients were first dichotomized according to the presence of a hematoma (ICH or ISH). Next, we performed a subgroup analysis comparing ICH versus ISH to explore their relationship with the most relevant demographic, clinical, and angioarchitectural features. Results: Overall, 85 patients (52%) had a pure SAH, and 78 (48%) had presented with an associated ICH or ISH. No significant differences were observed in the demographics or angioarchitectural features between the 2 groups. However, the Fisher grade and Hunt-Hess score were higher for the patients with hematomas. A good outcome was observed in a higher percentage of patients with pure SAH compared with those with an associated hematoma (76% vs. 44%), although the mortality rates were comparable. Age, Hunt-Hess score, and treatment-related complications were the main outcome predictors on multivariate analysis. Patients with ICH appeared worse clinically compared with those with ISH. We also found that older age, a higher Hunt-Hess score, larger aneurysms, decompressive craniectomy, and treatment-related complications were associated with poor outcomes among the patients with an ISH, but not an ICH, which appeared, per se, as a more severe clinical condition. Conclusions: Our study has confirmed that age, Hunt-Hess score, and treatment-related complications influence the outcome of patients with ruptured MCA aneurysms. However, in the subgroup analysis of patients with SAH associated with an ICH or ISH, only the Hunt-Hess score at onset appeared as an independent predictor of the outcome.

Comparison Between Intrasylvian and Intracerebral Hematoma Associated with Ruptured Middle Cerebral Artery Aneurysms: Clinical Implications, Technical Considerations, and Outcome Evaluation / Lucio Sturiale, Carmelo; Scerrati, Alba; Ricciardi, Luca; Rustemi, Oriela; Maria Auricchio, Anna; Norri, Nicolò; Piazza, Amedeo; Ranieri, Fabio; Benato, Alberto; Tomatis, Alberto; Albanese, Alessio; Mangiola, Annunziato; Di Egidio, Vincenzo; Carlo Zotta, Donato; Farneti, Marco; Marchese, Enrico; Raco, Antonino; Volpin, Lorenzo; Trevisi, Gianluca. - In: WORLD NEUROSURGERY. - ISSN 1878-8750. - (2023). [10.1016/j.wneu.2023.03.024]

Comparison Between Intrasylvian and Intracerebral Hematoma Associated with Ruptured Middle Cerebral Artery Aneurysms: Clinical Implications, Technical Considerations, and Outcome Evaluation

Luca Ricciardi;Amedeo Piazza;Alessio Albanese;Antonino Raco;
2023

Abstract

Background: Subarachnoid hemorrhage (SAH) due to a middle cerebral artery (MCA) aneurysm rupture is often associated with an intracerebral hematoma (ICH) or intrasylvian hematoma (ISH). Methods: We reviewed 163 patients with ruptured MCA aneurysms associated with pure SAH or SAH plus ICH or ISH. The patients were first dichotomized according to the presence of a hematoma (ICH or ISH). Next, we performed a subgroup analysis comparing ICH versus ISH to explore their relationship with the most relevant demographic, clinical, and angioarchitectural features. Results: Overall, 85 patients (52%) had a pure SAH, and 78 (48%) had presented with an associated ICH or ISH. No significant differences were observed in the demographics or angioarchitectural features between the 2 groups. However, the Fisher grade and Hunt-Hess score were higher for the patients with hematomas. A good outcome was observed in a higher percentage of patients with pure SAH compared with those with an associated hematoma (76% vs. 44%), although the mortality rates were comparable. Age, Hunt-Hess score, and treatment-related complications were the main outcome predictors on multivariate analysis. Patients with ICH appeared worse clinically compared with those with ISH. We also found that older age, a higher Hunt-Hess score, larger aneurysms, decompressive craniectomy, and treatment-related complications were associated with poor outcomes among the patients with an ISH, but not an ICH, which appeared, per se, as a more severe clinical condition. Conclusions: Our study has confirmed that age, Hunt-Hess score, and treatment-related complications influence the outcome of patients with ruptured MCA aneurysms. However, in the subgroup analysis of patients with SAH associated with an ICH or ISH, only the Hunt-Hess score at onset appeared as an independent predictor of the outcome.
2023
Hematoma; ICH; Intracerebral; Intrasylvian; Middle cerebral artery; SAH; Subarachnoid hemorrhage
01 Pubblicazione su rivista::01a Articolo in rivista
Comparison Between Intrasylvian and Intracerebral Hematoma Associated with Ruptured Middle Cerebral Artery Aneurysms: Clinical Implications, Technical Considerations, and Outcome Evaluation / Lucio Sturiale, Carmelo; Scerrati, Alba; Ricciardi, Luca; Rustemi, Oriela; Maria Auricchio, Anna; Norri, Nicolò; Piazza, Amedeo; Ranieri, Fabio; Benato, Alberto; Tomatis, Alberto; Albanese, Alessio; Mangiola, Annunziato; Di Egidio, Vincenzo; Carlo Zotta, Donato; Farneti, Marco; Marchese, Enrico; Raco, Antonino; Volpin, Lorenzo; Trevisi, Gianluca. - In: WORLD NEUROSURGERY. - ISSN 1878-8750. - (2023). [10.1016/j.wneu.2023.03.024]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1677069
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