Treatment of gliomas: a changing landscape

In the past, the Central Nervous System Editors have examined changes in radiation oncology and they continue their efforts in this Oncology Scan on gliomas. For many years, surgery and radiation therapy have played a significant role in the treatment of patients with glioma. Chemotherapy was shown to provide a survival benefit when added to radiation therapy for patients with glioblastoma in 2005 and anaplastic oligodendroglioma in 2013. In the past decade the standard of care for glioma patients has largely remained the same. However, in the past year multiple practice-changing randomized trials in glioma have been published. In this Oncology Scan, we highlight 3 such trials to address how they may impact treatment.