Benign and malignant thyroid diseases (TDs) have been associated with the occurrence of extrathyroidal malignancies (EMs), including colorectal cancers (CRCs). Such associations have generated a major interest, as their characterization may provide useful clues regarding diseases’ etiology and/or progression, with the possible identification of shared congenital and environmental elements. On the other hand, elucidation of the underlying molecular mechanism(s) could lead to an improved and tailored clinical management of these patients and stimulate an increased surveillance of TD patients at higher threat of developing EMs. Here, we will examine the epidemiological, clinical, and molecular findings connecting TD and CRC, with the aim to identify possible molecular mechanism(s) responsible for such diseases’ relationship.

Insights on the association between thyroid diseases and colorectal cancer / Gagliardi, Federica; Baldini, Enke; Lori, Eleonora; Cardarelli, Silvia; Pironi, Daniele; Lauro, Augusto; Tripodi, Domenico; Palumbo, Piergaspare; D'Armiento, Eleonora; Cavallaro, Giuseppe; Polistena, Andrea; D'Orazi, Valerio; Sibio, Simone; Fallahi, Poupak; Antonelli, Alessandro; D'Andrea, Vito; Ulisse, Salvatore; Sorrenti, Salvatore. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 12:6(2023). [10.3390/jcm12062234]

Insights on the association between thyroid diseases and colorectal cancer

Federica Gagliardi
Co-primo
;
Enke Baldini
Co-primo
;
Eleonora Lori
Secondo
;
Silvia Cardarelli;Daniele Pironi;Augusto Lauro;Domenico Tripodi;Piergaspare Palumbo;Eleonora D’Armiento;Giuseppe Cavallaro;Andrea Polistena;Valerio D'Orazi;simone sibio;Alessandro Antonelli;VITO D'ANDREA;Salvatore Ulisse
Penultimo
;
Salvatore SORRENTI
Ultimo
2023

Abstract

Benign and malignant thyroid diseases (TDs) have been associated with the occurrence of extrathyroidal malignancies (EMs), including colorectal cancers (CRCs). Such associations have generated a major interest, as their characterization may provide useful clues regarding diseases’ etiology and/or progression, with the possible identification of shared congenital and environmental elements. On the other hand, elucidation of the underlying molecular mechanism(s) could lead to an improved and tailored clinical management of these patients and stimulate an increased surveillance of TD patients at higher threat of developing EMs. Here, we will examine the epidemiological, clinical, and molecular findings connecting TD and CRC, with the aim to identify possible molecular mechanism(s) responsible for such diseases’ relationship.
2023
thyroid; hypothyroidism; hyperthyroidism; colorectal cancer
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Insights on the association between thyroid diseases and colorectal cancer / Gagliardi, Federica; Baldini, Enke; Lori, Eleonora; Cardarelli, Silvia; Pironi, Daniele; Lauro, Augusto; Tripodi, Domenico; Palumbo, Piergaspare; D'Armiento, Eleonora; Cavallaro, Giuseppe; Polistena, Andrea; D'Orazi, Valerio; Sibio, Simone; Fallahi, Poupak; Antonelli, Alessandro; D'Andrea, Vito; Ulisse, Salvatore; Sorrenti, Salvatore. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 12:6(2023). [10.3390/jcm12062234]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1674683
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