In this paper, we provide evidence that Zn2+ ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments.
The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin / Botticelli, S., Chiaraluce, R., Consalvi, V., La Penna, G., Pasquo, A., Petrosino, M., Proux, O., Rossi, G.C., Stellato, F., Morante, S.. - In: THE EUROPEAN PHYSICAL JOURNAL PLUS. - ISSN 2190-5444. - 138:216(2023). [10.1140/epjp/s13360-023-03731-w]
The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
R. Chiaraluce;V. Consalvi;M. Petrosino;
2023
Abstract
In this paper, we provide evidence that Zn2+ ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments.| File | Dimensione | Formato | |
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Botticelli_The role of Zn_2023.pdf
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