Making decisions based on the actions of others is critical to daily interpersonal interactions. We investigated the representations of other's actions at single neural level in posterior medial prefrontal cortex (pmPFC) in two monkeys during the observation of actions of another agent, in a social interaction task. Each monkey separately interacted with a human partner. The monkey and the human alternated turns as actor and observer. The actor was required to reach one of two visual targets, avoiding the previously chosen target, while the observer monitored that action. pmPFC neurons decoupled in most cases self from others during both the execution and the observation of explicit actions. pmPFC neurons showed selective directional tuning specific for the agent who was executing the task. Moreover, we assessed the relationship of the response coding between the periods immediately before and after the action, by using a cross-modal decoding analysis. We found neural network stability from the action anticipation period to the observation of other's actions, suggesting a strong relationship between the anticipation and the execution of an action. When the monkey was the actor, the population coding appeared dynamic, possibly reflecting a goal-action transformation unique to the monkey's own action execution.

Neural representation of others during action observation in posterior medial prefrontal cortex / Falcone, Rossella; Cirillo, Rossella; Ceccarelli, Francesco; Genovesio, Aldo. - In: CEREBRAL CORTEX. - ISSN 1047-3211. - 32:20(2022), pp. 4512-4523. [10.1093/cercor/bhab499]

Neural representation of others during action observation in posterior medial prefrontal cortex

Falcone, Rossella
Primo
Membro del Collaboration Group
;
Cirillo, Rossella
Membro del Collaboration Group
;
Ceccarelli, Francesco
Membro del Collaboration Group
;
Genovesio, Aldo
Ultimo
Funding Acquisition
2022

Abstract

Making decisions based on the actions of others is critical to daily interpersonal interactions. We investigated the representations of other's actions at single neural level in posterior medial prefrontal cortex (pmPFC) in two monkeys during the observation of actions of another agent, in a social interaction task. Each monkey separately interacted with a human partner. The monkey and the human alternated turns as actor and observer. The actor was required to reach one of two visual targets, avoiding the previously chosen target, while the observer monitored that action. pmPFC neurons decoupled in most cases self from others during both the execution and the observation of explicit actions. pmPFC neurons showed selective directional tuning specific for the agent who was executing the task. Moreover, we assessed the relationship of the response coding between the periods immediately before and after the action, by using a cross-modal decoding analysis. We found neural network stability from the action anticipation period to the observation of other's actions, suggesting a strong relationship between the anticipation and the execution of an action. When the monkey was the actor, the population coding appeared dynamic, possibly reflecting a goal-action transformation unique to the monkey's own action execution.
2022
medial prefrontal cortex; monkeys; neural dynamics; social interactions
01 Pubblicazione su rivista::01a Articolo in rivista
Neural representation of others during action observation in posterior medial prefrontal cortex / Falcone, Rossella; Cirillo, Rossella; Ceccarelli, Francesco; Genovesio, Aldo. - In: CEREBRAL CORTEX. - ISSN 1047-3211. - 32:20(2022), pp. 4512-4523. [10.1093/cercor/bhab499]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1669091
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