Translation of electron FLASH radiotherapy in clinical practice requires the use of high energy accelerators to treat deep tumours and Very High Electron Energy (VHEE) could represent a valid technique to achieve this goal. In this scenario, a VHEE FLASH linac is under study at the University La Sapienza of Rome (Italy) in collaboration with the Italian Institute for Nuclear Research (INFN) and the Institut Curie (France). Here we present the preliminary results of a compact C-band system aiming to reach an high accelerating gradient and an high pulse current necessary to deliver high dose per pulse and ultra-high dose rate required for FLASH effect. We propose a system composed of a low energy high current injector linac followed by a modular section of high accelerating gradient structures. CST code is used to define the required LINAC’s RF parameters and beam dynamics simulations are performed using TSTEP and ASTRA

Proposal of a VHEE Linac for FLASH radiotherapy / Giuliano, L; Bosco, F; Carillo, M; Arcangelis, D De; Ficcadenti, L; Francescone, D; Gregorio, A De; Franciosini, G; Migliorati, M; Mostacci, A; Palumbo, L; Patera, V; Sarti, A; Alesini, D; Behtouei, M; Faillace, L; Gallo, A; Spataro, B; Vannozzi, A; Cirrone, P; Cuttone, G; Torrisi, G; Bisogni, M G; Pensavalle, J H; Martino, F Di; Favaudon, V; Heinrich, S; Patriarca, A. - In: JOURNAL OF PHYSICS. CONFERENCE SERIES. - ISSN 1742-6588. - 2420:1(2023), p. 012087. (Intervento presentato al convegno IPAC International Particle Accelerator Conference tenutosi a Bangkok Thailand) [10.1088/1742-6596/2420/1/012087].

Proposal of a VHEE Linac for FLASH radiotherapy

Giuliano, L;Bosco, F;Carillo, M;Ficcadenti, L;Francescone, D;Gregorio, A De;Franciosini, G;Migliorati, M;Mostacci, A;Palumbo, L;Patera, V;Sarti, A;Alesini, D;Behtouei, M;Faillace, L;Spataro, B;Vannozzi, A;Favaudon, V;Patriarca, A
2023

Abstract

Translation of electron FLASH radiotherapy in clinical practice requires the use of high energy accelerators to treat deep tumours and Very High Electron Energy (VHEE) could represent a valid technique to achieve this goal. In this scenario, a VHEE FLASH linac is under study at the University La Sapienza of Rome (Italy) in collaboration with the Italian Institute for Nuclear Research (INFN) and the Institut Curie (France). Here we present the preliminary results of a compact C-band system aiming to reach an high accelerating gradient and an high pulse current necessary to deliver high dose per pulse and ultra-high dose rate required for FLASH effect. We propose a system composed of a low energy high current injector linac followed by a modular section of high accelerating gradient structures. CST code is used to define the required LINAC’s RF parameters and beam dynamics simulations are performed using TSTEP and ASTRA
2023
IPAC International Particle Accelerator Conference
Flash; radiotherapy; Linac; radiation
04 Pubblicazione in atti di convegno::04c Atto di convegno in rivista
Proposal of a VHEE Linac for FLASH radiotherapy / Giuliano, L; Bosco, F; Carillo, M; Arcangelis, D De; Ficcadenti, L; Francescone, D; Gregorio, A De; Franciosini, G; Migliorati, M; Mostacci, A; Palumbo, L; Patera, V; Sarti, A; Alesini, D; Behtouei, M; Faillace, L; Gallo, A; Spataro, B; Vannozzi, A; Cirrone, P; Cuttone, G; Torrisi, G; Bisogni, M G; Pensavalle, J H; Martino, F Di; Favaudon, V; Heinrich, S; Patriarca, A. - In: JOURNAL OF PHYSICS. CONFERENCE SERIES. - ISSN 1742-6588. - 2420:1(2023), p. 012087. (Intervento presentato al convegno IPAC International Particle Accelerator Conference tenutosi a Bangkok Thailand) [10.1088/1742-6596/2420/1/012087].
File allegati a questo prodotto
File Dimensione Formato  
Mostacci_FLASH radiotherapy_2023.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 814.36 kB
Formato Adobe PDF
814.36 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1667482
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? ND
social impact