Background Stimulating the cerebellum with transcranial magnetic stimulation is often perceived as uncomfortable. No study has systematically tested which coil design can effectively trigger a cerebellar response with the least discomfort. Objective To determine the relationship between perceived discomfort and effectiveness of cerebellar stimulation using different coils: MagStim (70 mm, 110 mm-coated, 110-uncoated), MagVenture and Deymed. Methods Using the cerebellar-brain inhibition (CBI) protocol, we conducted a CBI recruitment curve with respect to each participant’s maximum tolerated-stimulus intensity (MTI) to assess how effective each coil was at activating the cerebellum. Results Only the Deymed double-cone coil elicited CBI at low intensities (−20% MTI). At the MTI, the MagStim (110 mm coated/uncoated) and Deymed coils produced reliable CBI, whereas no CBI was found with the MagVenture coil. Conclusions: The Deymed double-cone coil was most effective at cerebellar stimulation at tolerable intensities. These results can guide coil selection and stimulation parameters when designing cerebellar TMS studies.

Cerebellar Transcranial Magnetic Stimulation: The Role of Coil Type from Distinct Manufacturers / Spampinato, Danny Adrian; Ibáñez, Jaime; Spanoudakis, Manos; Hammond, Paul; Rothwell, John C.. - In: BRAIN STIMULATION. - ISSN 1935-861X. - (2019). [10.1016/j.brs.2019.09.005]

Cerebellar Transcranial Magnetic Stimulation: The Role of Coil Type from Distinct Manufacturers

Danny Spampinato
;
2019

Abstract

Background Stimulating the cerebellum with transcranial magnetic stimulation is often perceived as uncomfortable. No study has systematically tested which coil design can effectively trigger a cerebellar response with the least discomfort. Objective To determine the relationship between perceived discomfort and effectiveness of cerebellar stimulation using different coils: MagStim (70 mm, 110 mm-coated, 110-uncoated), MagVenture and Deymed. Methods Using the cerebellar-brain inhibition (CBI) protocol, we conducted a CBI recruitment curve with respect to each participant’s maximum tolerated-stimulus intensity (MTI) to assess how effective each coil was at activating the cerebellum. Results Only the Deymed double-cone coil elicited CBI at low intensities (−20% MTI). At the MTI, the MagStim (110 mm coated/uncoated) and Deymed coils produced reliable CBI, whereas no CBI was found with the MagVenture coil. Conclusions: The Deymed double-cone coil was most effective at cerebellar stimulation at tolerable intensities. These results can guide coil selection and stimulation parameters when designing cerebellar TMS studies.
2019
Cerebellum; Transcranial magnetic stimulation; Cerebellar-M1 Connectivity
01 Pubblicazione su rivista::01a Articolo in rivista
Cerebellar Transcranial Magnetic Stimulation: The Role of Coil Type from Distinct Manufacturers / Spampinato, Danny Adrian; Ibáñez, Jaime; Spanoudakis, Manos; Hammond, Paul; Rothwell, John C.. - In: BRAIN STIMULATION. - ISSN 1935-861X. - (2019). [10.1016/j.brs.2019.09.005]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1665250
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