Objective: To report the effect of metformin treatment on a patient with recurrent miscarriage (RM) andpolycystic ovary syndrome (PCOS).Design: Case report.Setting: University department of obstetrics and gynecology, Italy.Patient(s): A woman complaining of RM who had PCOS and insulin resistance.Intervention(s): Clinical, biochemical, and instrumental assessments.Main Outcome Measure(s): Administration of metformin hydrochloride before and throughout pregnancy.Result(s): After 3 months of treatment, the patient became pregnant. The pregnancy had a physiologicdevelopment, and at 39 weeks of gestation, the patient spontaneously delivered a healthy infant.Conclusion(s): Metformin has shown to be effective in an insulin-resistant PCOS woman with RM. (Fertil Steril (R)2006;85:1511.e3-5. (c) 2006 by American Society for Reproductive Medicine.)
Metformin hydrochloride and recurrent miscarriage in a woman with polycystic ovary syndrome / Palomba, Stefano; Falbo, Angela; Orio, Francesco; Russo, Tiziana; Tolino, Achille; Zullo, Fulvio. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - 85:5(2006), pp. 1511.e3-1511.e5. [10.1016/j.fertnstert.2005.09.063]
Metformin hydrochloride and recurrent miscarriage in a woman with polycystic ovary syndrome
Palomba, Stefano;
2006
Abstract
Objective: To report the effect of metformin treatment on a patient with recurrent miscarriage (RM) andpolycystic ovary syndrome (PCOS).Design: Case report.Setting: University department of obstetrics and gynecology, Italy.Patient(s): A woman complaining of RM who had PCOS and insulin resistance.Intervention(s): Clinical, biochemical, and instrumental assessments.Main Outcome Measure(s): Administration of metformin hydrochloride before and throughout pregnancy.Result(s): After 3 months of treatment, the patient became pregnant. The pregnancy had a physiologicdevelopment, and at 39 weeks of gestation, the patient spontaneously delivered a healthy infant.Conclusion(s): Metformin has shown to be effective in an insulin-resistant PCOS woman with RM. (Fertil Steril (R)2006;85:1511.e3-5. (c) 2006 by American Society for Reproductive Medicine.)I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
