Purpose of reviewTo review the current reproductive advances in insulin-sensitizing agents for treatment of polycystic ovary syndrome patients.Recent findingsTo date, among insulin-sensitizing drugs, only metformin should be used to improve reproductive function in well selected polycystic ovary syndrome patients. Preliminary data seem to show beneficial effects of thiazolidinediones in improving metabolic and hormonal patterns and in restoring regular menses.SummaryThe use of insulin-sensitizing drugs offers a new perspective for the treatment of polycystic ovary syndrome-related reproductive disorders. However, further data are needed before we can draw definitive conclusions regarding their clinical role.
Insulin-sensitizing agents and reproductive function in polycystic ovary syndrome patients / Palomba, Stefano; Falbo, Angela; Orio, Francesco; Zullo, Fulvio. - In: CURRENT OPINION IN OBSTETRICS & GYNECOLOGY. - ISSN 1040-872X. - 20:4(2008), pp. 364-373. [10.1097/GCO.0b013e328307ebc5]
Insulin-sensitizing agents and reproductive function in polycystic ovary syndrome patients
Palomba, Stefano
;
2008
Abstract
Purpose of reviewTo review the current reproductive advances in insulin-sensitizing agents for treatment of polycystic ovary syndrome patients.Recent findingsTo date, among insulin-sensitizing drugs, only metformin should be used to improve reproductive function in well selected polycystic ovary syndrome patients. Preliminary data seem to show beneficial effects of thiazolidinediones in improving metabolic and hormonal patterns and in restoring regular menses.SummaryThe use of insulin-sensitizing drugs offers a new perspective for the treatment of polycystic ovary syndrome-related reproductive disorders. However, further data are needed before we can draw definitive conclusions regarding their clinical role.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


