Essential tremor (ET) is one of the most common movement disorders. Over the last 10 years, magnetic resonance imaging (MRI) has shed light on the structural and functional abnormalities possibly involved in ET pathophysiology. In this systematic review, we aimed to identify the cortical and subcortical structures involved and the role that different brain areas play in the pathophysiology of motor and non-motor ET features. We found that structural (grey and white matter) cerebellar damage and connectivity alterations between the cerebellum and various cortical areas play a role in both motor and non-motor symptoms of ET. In particular, many studies found an association between MRI findings and non-motor symptoms.

The Contribution of Neuroimaging to the Understanding of Essential Tremor Pathophysiology: a Systematic Review / Pietracupa, Sara; Bologna, Matteo; Tommasin, Silvia; Berardelli, Alfredo; Pantano, Patrizia. - In: THE CEREBELLUM. - ISSN 1473-4222. - (2022).

The Contribution of Neuroimaging to the Understanding of Essential Tremor Pathophysiology: a Systematic Review

Sara Pietracupa;Matteo Bologna;Silvia Tommasin;Alfredo Berardelli;Patrizia Pantano
2022

Abstract

Essential tremor (ET) is one of the most common movement disorders. Over the last 10 years, magnetic resonance imaging (MRI) has shed light on the structural and functional abnormalities possibly involved in ET pathophysiology. In this systematic review, we aimed to identify the cortical and subcortical structures involved and the role that different brain areas play in the pathophysiology of motor and non-motor ET features. We found that structural (grey and white matter) cerebellar damage and connectivity alterations between the cerebellum and various cortical areas play a role in both motor and non-motor symptoms of ET. In particular, many studies found an association between MRI findings and non-motor symptoms.
2022
Essential tremor; Grey matter; MRI functional; Magnetic resonance imaging; Systematic review; White matter.
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
The Contribution of Neuroimaging to the Understanding of Essential Tremor Pathophysiology: a Systematic Review / Pietracupa, Sara; Bologna, Matteo; Tommasin, Silvia; Berardelli, Alfredo; Pantano, Patrizia. - In: THE CEREBELLUM. - ISSN 1473-4222. - (2022).
File allegati a questo prodotto
File Dimensione Formato  
The Contribution of Neuroimaging to the Understanding of Essential Tremor Pathophysiology- a Systematic Review.pdf

accesso aperto

Note: Pietracupa_The Contribution of Neuroimaging_2022
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 1.41 MB
Formato Adobe PDF
1.41 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1662639
Citazioni
  • ???jsp.display-item.citation.pmc??? 8
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 9
social impact