Hyperkinesias are heterogeneous involuntary movements that significantly differ in terms of clinical and semeiological manifestations, including rhythm, regularity, speed, duration, and other factors that determine their appearance or suppression. Hyperkinesias are due to complex, variable, and largely undefined pathophysiological mechanisms that may involve different brain areas. In this chapter, we specifically focus on dystonia, chorea and hemiballismus, and other dyskinesias, specifically, levodopa-induced, tardive, and cranial dyskinesia. We address the role of neurophysiological studies aimed at explaining the pathophysiology of these conditions. We mainly refer to human studies using surface and invasive indepth recordings, as well as spinal, brainstem, and transcortical reflexology and non-invasive brain stimulation techniques. We discuss the extent to which the neurophysiological abnormalities observed in hyperkinesias may be explained by pathophysiological models. We highlight the most relevant issues that deserve future research efforts. The potential role of neurophysiological assessment in the clinical context of hyperkinesia is also discussed. CO 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

Dystonia, chorea, hemiballismus and other dyskinesias / Bologna, M.; Valls-Sole, J.; Kamble, N.; Pal, P. K.; Conte, A.; Guerra, A.; Belvisi, D.; Berardelli, A.. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1872-8952. - 140:(2022), pp. 110-125. [10.1016/j.clinph.2022.05.014]

Dystonia, chorea, hemiballismus and other dyskinesias

Bologna M.;Conte A.;Guerra A.;Belvisi D.;Berardelli A.
2022

Abstract

Hyperkinesias are heterogeneous involuntary movements that significantly differ in terms of clinical and semeiological manifestations, including rhythm, regularity, speed, duration, and other factors that determine their appearance or suppression. Hyperkinesias are due to complex, variable, and largely undefined pathophysiological mechanisms that may involve different brain areas. In this chapter, we specifically focus on dystonia, chorea and hemiballismus, and other dyskinesias, specifically, levodopa-induced, tardive, and cranial dyskinesia. We address the role of neurophysiological studies aimed at explaining the pathophysiology of these conditions. We mainly refer to human studies using surface and invasive indepth recordings, as well as spinal, brainstem, and transcortical reflexology and non-invasive brain stimulation techniques. We discuss the extent to which the neurophysiological abnormalities observed in hyperkinesias may be explained by pathophysiological models. We highlight the most relevant issues that deserve future research efforts. The potential role of neurophysiological assessment in the clinical context of hyperkinesia is also discussed. CO 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.
2022
Athetosis; Ballismus; Chorea; Dyskinesias; Dystonia; Hyperkinesia; Pathophysiology; Humans; Levodopa; Chorea; Dyskinesias; Dystonia; Dystonic Disorders
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Dystonia, chorea, hemiballismus and other dyskinesias / Bologna, M.; Valls-Sole, J.; Kamble, N.; Pal, P. K.; Conte, A.; Guerra, A.; Belvisi, D.; Berardelli, A.. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1872-8952. - 140:(2022), pp. 110-125. [10.1016/j.clinph.2022.05.014]
File allegati a questo prodotto
File Dimensione Formato  
49.Bologna et al., 2022. CLINPH.pdf

solo gestori archivio

Tipologia: Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 307.84 kB
Formato Adobe PDF
307.84 kB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1660558
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 4
social impact